Kahweol eicosanate (CAS 108214-32-0)

Kahweol eicosanate, identified by the CAS number 108214-32-0, is a chemically modified derivative of kahweol, which is one of the naturally occurring diterpenes found primarily in coffee beans. This compound has an eicosanoic acid ester group attached, significantly altering its physical and chemical properties compared to its parent compound. In research, kahweol eicosanate is employed to study the bioactivity and stability of diterpene esters, providing insights into how structural modifications can affect the behavior and interaction of these molecules within biological systems. The introduction of the long-chain eicosanate moiety is particularly useful for investigating the lipophilicity and membrane interaction characteristics of the compound. This modification often results in enhanced binding affinity and interaction with lipid bilayers, which is critical for understanding the cellular uptake, distribution, and localization of such compounds. Additionally, kahweol eicosanate serves as a model to explore the mechanisms by which diterpenes can influence cellular signaling pathways indirectly through membrane dynamics or directly through receptor-mediated pathways. The research findings contribute to a broader understanding of the role of structurally diverse lipids in cellular processes and their potential implications in cellular signaling and regulation.