Molecular structure of K11777, CAS Number: 233277-99-1
K777 (CAS 233277-99-1)
CAS Number:
233277-99-1
Molecular Weight:
574.73
Molecular Formula:
C32H38N4O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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K777 (CAS 233277-99-1) References
- In vitro evaluation of the disposition of A novel cysteine protease inhibitor. | Jacobsen, W., et al. 2000. Drug Metab Dispos. 28: 1343-51. PMID: 11038163
- Schistosomiasis mansoni: novel chemotherapy using a cysteine protease inhibitor. | Abdulla, MH., et al. 2007. PLoS Med. 4: e14. PMID: 17214506
- Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei. | Yang, PY., et al. 2012. Chem Commun (Camb). 48: 835-7. PMID: 22124229
- Cure of hookworm infection with a cysteine protease inhibitor. | Vermeire, JJ., et al. 2012. PLoS Negl Trop Dis. 6: e1680. PMID: 22802972
- A cysteine protease inhibitor rescues mice from a lethal Cryptosporidium parvum infection. | Ndao, M., et al. 2013. Antimicrob Agents Chemother. 57: 6063-73. PMID: 24060869
- Evaluation of trypanocidal activity of combinations of anti-sleeping sickness drugs with cysteine protease inhibitors. | Steverding, D. 2015. Exp Parasitol. 151-152: 28-33. PMID: 25662707
- Protease inhibitors targeting coronavirus and filovirus entry. | Zhou, Y., et al. 2015. Antiviral Res. 116: 76-84. PMID: 25666761
- Leishmanicidal therapy targeted to parasite proteases. | Machado, PA., et al. 2019. Life Sci. 219: 163-181. PMID: 30641084
- Extracellular Cysteine Proteases of Key Intestinal Protozoan Pathogens-Factors Linked to Virulence and Pathogenicity. | Argüello-García, R., et al. 2023. Int J Mol Sci. 24: PMID: 37629029
Inhibitor of:
2310051M13Rik, 8030411F24Rik, Cathepsin, cathepsin A, cathepsin B, cathepsin L, cathepsin S, Chymostatin, cystatin SN, PERP (p53 apoptosis effector related to PMP22), POP2, stefin A1L1, stefin A2, and stefin A2l1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
K777, 10 mg | sc-507382 | 10 mg | $566.00 |