Molecular structure of JX-401, CAS Number: 349087-34-9
JX-401 (CAS 349087-34-9)
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Alternate Names:
1-[2-Methoxy-4-(methylthio)benzoyl]-4-(phenylmethyl)piperidine
Application:
JX-401 is a potent non-cytotoxic cell membrane permeable p38α inhibitor
CAS Number:
349087-34-9
Purity:
≥95%
Molecular Weight:
355.49
Molecular Formula:
C21H25NO2S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
JX-401 is a potent non-cytotoxic cell membrane permeable p38alpha inhibitor that acts by reversibly binding MAPK p38alpha. Yet it is non functional against p38gamma. Shown to inhibit ion channels that are activated by p38 MAP kinase and has been purified to >95% purity. Used to study protein interactions and ligand-receptor binding.
JX-401 (CAS 349087-34-9) References
- JX401, A p38alpha inhibitor containing a 4-benzylpiperidine motif, identified via a novel screening system in yeast. | Friedmann, Y., et al. 2006. Mol Pharmacol. 70: 1395-405. PMID: 16847144
Inhibitor of:
p38 alpha, and Ser/Thr Protein Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
JX-401, 1 mg | sc-200687 | 1 mg | $62.00 | |||
JX-401, 10 mg | sc-200687A | 10 mg | $131.00 |