Jurkat Cell Lysate for Immunoprecipaitation: sc-24788

Jurkat (IP) Cell Lysate is derived from Jurkat cells, which are an immortalized line of human T lymphocytes often used in immunological research due to their origin from a T-cell leukemia. The "IP" in the lysate's name indicates that the lysate is prepared specifically for use in immunoprecipitation (IP) experiments, a technique used to isolate and concentrate specific proteins from the lysate via antibody binding. This specialized preparation involves treating the Jurkat cells under conditions that preserve protein-protein interactions and maintain the native state of proteins, making it ideal for studying dynamic cellular interactions and signaling pathways. Researchers use Jurkat (IP) Cell Lysate to investigate various aspects of T-cell signaling, including activation, proliferation, and apoptosis. The lysate provides a rich source of T-cell specific proteins and interacting partners, allowing for the detailed analysis of protein complexes and post-translational modifications that occur in response to various stimuli. By using this lysate in IP experiments, scientists can pull down specific proteins of interest and their associated molecules, facilitating the study of complex biochemical pathways in T-cell biology and providing insights into the molecular mechanisms that underlie cellular function and regulation. This approach is crucial for advancing our understanding of immune cell behavior and signaling under various physiological conditions.