Jurkat + hydrogen peroxide Cell Lysate: sc-24714

Jurkat + Hydrogen Peroxide Cell Lysate is obtained from Jurkat cells, an immortalized line of human T lymphocytes, which have been treated with hydrogen peroxide to induce oxidative stress. This treatment is a common method for studying the cellular responses to reactive oxygen species (ROS), which play a crucial role in cell signaling and homeostasis. By exposing Jurkat cells to hydrogen peroxide, researchers activate pathways involved in oxidative stress response, including those related to detoxification, repair, and apoptosis. The lysate produced from these treated cells contains a wide array of biomolecules such as proteins, nucleic acids, and other cellular components that reflect the cellular state under oxidative stress. This lysate is extensively used in research to investigate the activation states of various signaling molecules, particularly those involved in the NF-kB pathway, stress response kinases like JNK and p38, and the mechanisms of cell death. By studying Jurkat + Hydrogen Peroxide Cell Lysate, scientists can gain deeper insights into the molecular mechanisms that cells employ to manage and mitigate damage caused by oxidative stress, which is crucial for understanding how cells maintain their integrity and functionality in hostile environments. This knowledge is pivotal for broader biological applications, including the study of aging and immune system responses.