Jurkat + AP Cell Lysate: sc-24712

Jurkat + AP Cell Lysate originates from the Jurkat cell line, a type of immortalized line of human T lymphocyte cells, which are commonly used to study T cell behavior and signaling. The "AP" in the name refers to an activator protein treatment, suggesting that these cells were stimulated with a specific activator protein prior to lysis to provoke specific cellular functions or signaling pathways. The lysate is produced by disrupting the Jurkat cells, thus releasing a wide array of cellular components, including proteins, RNA, and other molecular entities. This particular lysate is especially useful in research focused on understanding T cell activation and the cellular mechanisms underpinning immune responses. Scientists employ Jurkat + AP Cell Lysate in various experimental settings, such as Western blotting, to analyze protein expression and modifications post-activation, or in co-immunoprecipitation experiments to study protein-protein interactions within activated T cells. Additionally, it provides insights into the pathways involved in cell proliferation, apoptosis, and signaling, making it a valuable resource for uncovering the intricacies of immune cell regulation and function in a controlled experimental context. This lysate serves as a vital tool for researchers aiming to dissect complex biochemical networks and cellular responses induced by specific stimuli.