Juglone (CAS 481-39-0)

Physical State :

Solid

Solubility :

Soluble in DMSO (10 mg/ml), ethanol (10 mg/ml), benzene (Freely soluble), chloroform (Freely soluble), ether, aqueous solution of alkalies, and hot water.

Storage :

Store at 4° C

Melting Point :

161-163° C (lit.)

Boiling Point :

~385.83° C at 760 mmHg (Predicted)

Density :

~1.4 g/cm³ (Predicted)

Refractive Index :

n²⁰_D 1.66

IC50 :

Indoleamine 2,3-dioxygenase: IC₅₀ = 1 µM (human); HaCaT (Keratinocytes): IC₅₀ = 0.8 µM (human); A2780 (Ovarian carcinoma cells): IC₅₀ = 1.4 µM (human); Dual specificity phosphatase Cdc25B: IC₅₀ = 19.8 µM (human); Dual specificity protein phosphatase 6: IC₅₀ = 12.4 µM (Rattus norvegicus); Dual specificity protein phosphatase 1: IC₅₀ = 13 µM (Mus musculus); Transcription in eukaryotic cells by RNA polymerase I: IC₅₀ = 7 µM; Transcription in eukaryotic cells by RNA polymerase II: IC₅₀ = 7 µM; Transcription in eukaryotic cells by RNA polymerase III: IC₅₀ = 2 µM

pK Values :

pK_a: 6.59

WGK Germany :

3

RTECS :

QJ5775000

PubChem CID :

Merck Index :

14: 5269

MDL Number :

MFCD00001684

EC Number :

207-567-5

Beilstein Registry :

1909764

SMILES :

C1=CC2=C(C(=O)C=CC2=O)C(=C1)O