JC-10
See product citations (3)
Alternate Names:
Enhanced JC-1
Application:
JC-10 is a mitochondria dye
Purity:
≥95%
Molecular Weight:
~600
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
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SDS & Certificate of Analysis
JC-10 is used to determine mitochondrial membrane potential. It is a cationic, lipophilicy dye often used in flow cytometry, fluorescence microscopy and microplate-based fluorescent assays. This dye changes color, from orange to green, as the membrane potential decreases. JC-10 is considered to be a superior analog of JC-1 iodide(sc-364116) due to it′s improved solubility in aqueous media as well as it′s ability to detect subtler changes in the mitochondrial membrane potential loss.
JC-10 References
- Improving anticancer efficacy of (-)-epigallocatechin-3-gallate gold nanoparticles in murine B16F10 melanoma cells. | Chen, CC., et al. 2014. Drug Des Devel Ther. 8: 459-74. PMID: 24855338
- Boosted Membrane Potential as Bioenergetic Response to Anoxia in Dinoroseobacter shibae. | Kirchhoff, C. and Cypionka, H. 2017. Front Microbiol. 8: 695. PMID: 28473821
- Use of Ratiometric Probes with a Spectrofluorometer for Bacterial Viability Measurement. | Cléach, J., et al. 2018. J Microbiol Biotechnol. 28: 1782-1790. PMID: 30562881
- Chronic Inflammatory-Modulating Potential of Cassia auriculata with Proinflammatory Cytokine IL-1beta and Its Anticancer Effect on Lung Cancer Cell Line. | Anitha, R., et al. 2021. Anticancer Agents Med Chem. 21: 343-354. PMID: 32781968
- Elevated cAMP Protects against Diclofenac-Induced Toxicity in Primary Rat Hepatocytes: A Protective Effect Mediated by the Exchange Protein Directly Activated by cAMP/cAMP-Regulated Guanine Nucleotide Exchange Factors. | Aguilar Mora, FA., et al. 2021. Mol Pharmacol. 99: 294-307. PMID: 33574047
- Dual Effects of Cyclooxygenase Inhibitors in Combination With CD19.CAR-T Cell Immunotherapy. | Yang, M., et al. 2021. Front Immunol. 12: 670088. PMID: 34122428
- Plumbagin Induces Cytotoxicity via Loss of Mitochondrial Membrane Potential and Caspase Activation in Metastatic Retinoblastoma. | Gharbaran, R., et al. 2021. Anticancer Res. 41: 4725-4732. PMID: 34593421
- FTH promotes the proliferation and renders the HCC cells specifically resist to ferroptosis by maintaining iron homeostasis. | Hu, W., et al. 2021. Cancer Cell Int. 21: 709. PMID: 34965856
- Garlic exosome-like nanoparticles reverse high-fat diet induced obesity via the gut/brain axis. | Sundaram, K., et al. 2022. Theranostics. 12: 1220-1246. PMID: 35154484
- JC-10 probe as a novel method for analyzing the mitochondrial membrane potential and cell stress in whole zebrafish embryos. | Younes, N., et al. 2022. Toxicol Res (Camb). 11: 77-87. PMID: 35237413
- Methods for mitochondrial health assessment by High Content Imaging System. | Panusatid, C., et al. 2022. MethodsX. 9: 101685. PMID: 35464807
- Ginsenoside Rk1 inhibits cell proliferation and promotes apoptosis in lung squamous cell carcinoma by calcium signaling pathway. | An, X., et al. 2019. RSC Adv. 9: 25107-25118. PMID: 35528653
- Effects of Sodium Pyruvate on Vanadyl Sulphate-Induced Reactive Species Generation and Mitochondrial Destabilisation in CHO-K1 Cells. | Zwolak, I. and Wnuk, E. 2022. Antioxidants (Basel). 11: PMID: 35624773
- Growth Differentiation Factor 15 Protects SH-SY5Y Cells From Rotenone-Induced Toxicity by Suppressing Mitochondrial Apoptosis. | Li, P., et al. 2022. Front Aging Neurosci. 14: 869558. PMID: 35721026
- Agonist-induced Piezo1 activation promote mitochondrial-dependent apoptosis in vascular smooth muscle cells. | Yin, Q., et al. 2022. BMC Cardiovasc Disord. 22: 287. PMID: 35751027
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
JC-10, 5 mg | sc-495909 | 5 mg | $290.00 |