JC-1 iodide (CAS 47729-63-5)
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JC-1 iodide is a fluorescent dye used to measure mitochondrial membrane potential in cells. It functions by accumulating in the mitochondria, where it forms aggregates in healthy cells with high membrane potential, emitting red fluorescence. In cells with low membrane potential, JC-1 iodide remains in its monomeric form, emitting green fluorescence. This allows to assess the health and functionality of mitochondria in various experimental applications. The mechanism of action involves the selective accumulation of JC-1 iodide in the mitochondria due to its lipophilic cationic nature, enabling the dye to respond to changes in membrane potential. By monitoring the shift in fluorescence from red to green to gain insights into mitochondrial function and assess the impact of different experimental conditions on cellular energetics. JC-1 iodide′s role in experimental applications involves providing a reliable indicator of mitochondrial health and function, allowing to study the effects of conditions on cellular metabolism and energy production.
JC-1 iodide (CAS 47729-63-5) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
JC-1 iodide, 5 mg | sc-495910 | 5 mg | $224.00 |