Molecular structure of Ivermectin monosaccharide, CAS Number: 123997-64-8
Ivermectin monosaccharide (CAS 123997-64-8)
See product citations (3)
Alternate Names:
Dihydroavermectin B1 monosaccharide; Ivermectin B1 monosaccharide
Application:
Ivermectin monosaccharide is a semi-synthetic potent inhibitor of nematode larval development
CAS Number:
123997-64-8
Purity:
>99%
Molecular Weight:
730.9
Molecular Formula:
C41H62O11
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ivermectin monosaccharide is a semi-synthetic potent inhibitor of nematode larval development that is devoid of paralytic activity. A part of the Avermectin family of 16-membered macrocyclic lactones derived from the actinomycete Streptomyces avermectinius which exhibit extraordinary anthelmintic activity. Exhibits potent inhibitory effects against nematode larval development, but does not exhibit paralytic activity. The monosaccharide form is used as a sensitive probe for the detection of select types of ivermectin resistance.
Ivermectin monosaccharide (CAS 123997-64-8) References
- Topical ivermectin: a new successful treatment for scabies. | Victoria, J. and Trujillo, R. 2001. Pediatr Dermatol. 18: 63-5. PMID: 11207977
- Ivermectin is better than benzyl benzoate for childhood scabies in developing countries. | Brooks, PA. and Grace, RF. 2002. J Paediatr Child Health. 38: 401-4. PMID: 12174005
- Effects of macrocyclic lactone anthelmintics on feeding and pharyngeal pumping in Trichostrongylus colubriformis in vitro. | Sheriff, JC., et al. 2002. Parasitology. 125: 477-84. PMID: 12458832
- An ivermectin-sensitive glutamate-gated chloride channel subunit from Dirofilaria immitis. | Yates, DM. and Wolstenholme, AJ. 2004. Int J Parasitol. 34: 1075-81. PMID: 15313134
- Larval development assay for detection of anthelmintic resistance in cyathostomins of Swedish horses. | Lind, EO., et al. 2005. Vet Parasitol. 128: 261-9. PMID: 15740863
- Ivermectin: pharmacology and application in dermatology. | Dourmishev, AL., et al. 2005. Int J Dermatol. 44: 981-8. PMID: 16409259
- Environmental impact of ivermectin excreted by cattle treated in autumn on dung fauna and degradation of faeces on pasture. | Iglesias, LE., et al. 2006. Parasitol Res. 100: 93-102. PMID: 16821034
- Interventions for treating scabies. | Strong, M. and Johnstone, P. 2007. Cochrane Database Syst Rev. 2007: CD000320. PMID: 17636630
- A new ivermectin formulation topically kills permethrin-resistant human head lice (Anoplura: Pediculidae). | Strycharz, JP., et al. 2008. J Med Entomol. 45: 75-81. PMID: 18283945
- New ventures in the genotoxic and cytotoxic effects of macrocyclic lactones, abamectin and ivermectin. | Molinari, G., et al. 2010. Cytogenet Genome Res. 128: 37-45. PMID: 20389039
- Avermectins and milbemycins against Fasciola hepatica: in vivo drug efficacy and in vitro receptor binding. | Shoop, WL., et al. 1995. Int J Parasitol. 25: 923-7. PMID: 8550292
- Use of two in vitro methods for the detection of benzimidazole resistance in equine small strongyles (Cyathostoma spp.). | Ihler, CF. and Bjørn, H. 1996. Vet Parasitol. 65: 117-25. PMID: 8916406
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ivermectin monosaccharide, 1 mg | sc-202190 | 1 mg | $300.00 |