Itraconazole-d9 (CAS 84625-61-6 (unlabeled))
Alternate Names:
(±)-4-[4-[4-[4-[[(2R,4S)-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl-d9)-3H-1,2,4-triazol-3-one
CAS Number:
84625-61-6 (unlabeled)
Molecular Weight:
714.69
Molecular Formula:
C35H29D9Cl2N8O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Itraconazole-d9 is a deuterated version of itraconazole, which is primarily used in scientific research to study the compound′s behavior and properties. The incorporation of deuterium atoms, which are heavier isotopes of hydrogen, allows researchers to use itraconazole-d9 as an internal standard in mass spectrometry. This facilitates more accurate quantification and analysis of itraconazole in various samples by providing a distinguishable mass difference. Moreover, itraconazole-d9 is employed in the investigation of metabolic pathways and the stability of itraconazole under different conditions, as the deuterium atoms can provide insights into the degradation processes and chemical interactions.
Itraconazole-d9 (CAS 84625-61-6 (unlabeled)) References
- Simultaneous determination of itraconazole and its CYP3A4-mediated metabolites including N-desalkyl itraconazole in human plasma using liquid chromatography-tandem mass spectrometry and its clinical application. | Imoto, Y., et al. 2020. J Pharm Health Care Sci. 6: 11. PMID: 32391164
- Pharmacokinetic Drug-Drug Interaction Studies Between Trilaciclib and Midazolam, Metformin, Rifampin, Itraconazole, and Topotecan in Healthy Volunteers and Patients with Extensive-Stage Small-Cell Lung Cancer. | Li, C., et al. 2022. Clin Drug Investig. 42: 679-692. PMID: 35842567
- Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer. | Marastoni, S., et al. 2022. Cancer Res Commun. 2: 293-306. PMID: 36875717
- Talaromyces marneffei infection and complicate manifestation of respiratory system in HIV-negative children. | Yang, Q., et al. 2023. BMC Pulm Med. 23: 100. PMID: 36978020
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| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Itraconazole-d9, 1 mg | sc-495557 | 1 mg | $311.00 |