ITD 1 (CAS 1099644-42-4)
Alternate Names:
4-[1,1′-biphenyl]-4-yl-1,4,5,6,7,8-hexahydro-2,7,7-trimethyl-5-oxo-3-quinolinecarboxylic acid, ethyl ester ITD1 ITD-1 idt 1
CAS Number:
1099644-42-4
Molecular Weight:
415.50
Molecular Formula:
C27H29NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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ITD 1 (CAS 1099644-42-4) References
- Small molecule-mediated TGF-β type II receptor degradation promotes cardiomyogenesis in embryonic stem cells. | Willems, E., et al. 2012. Cell Stem Cell. 11: 242-52. PMID: 22862949
- TGF-β sensu stricto signaling regulates skeletal morphogenesis in the sea urchin embryo. | Sun, Z. and Ettensohn, CA. 2017. Dev Biol. 421: 149-160. PMID: 27955944
- Hypoxia-inducible factor-1α activates transforming growth factor-β1/Smad signaling and increases collagen deposition in dermal fibroblasts. | Mingyuan, X., et al. 2018. Oncotarget. 9: 3188-3197. PMID: 29423039
- TGF-β induces GBM mesenchymal transition through upregulation of CLDN4 and nuclear translocation to activate TNF-α/NF-κB signal pathway. | Yan, T., et al. 2022. Cell Death Dis. 13: 339. PMID: 35418179
- SPSB1-mediated inhibition of TGF-β receptor-II impairs myogenesis in inflammation. | Li, Y., et al. 2023. J Cachexia Sarcopenia Muscle. 14: 1721-1736. PMID: 37209006
- Tripartite motif-containing 9 promoted proliferation and migration of bladder cancer cells through CEACAM6-Smad2/3 axis. | Zhang, ZC., et al. 2023. J Cell Commun Signal. 17: 1323-1333. PMID: 37249822
- Claudin-3 facilitates the progression and mediates the tumorigenic effects of TGF-β in glioblastoma multiforme. | Sun, Z., et al. 2023. Med Oncol. 40: 268. PMID: 37578554
- TCF12 regulates the TGF-β/Smad2/3 signaling pathway to accelerate the progression of osteoarthritis by targeting CXCR4. | Zheng, H., et al. 2024. J Orthop Translat. 44: 35-46. PMID: 38235367
- DUSP22 Ameliorates Endothelial-to-Mesenchymal Transition in HUVECs through Smad2/3 and MAPK Signaling Pathways. | Chen, L., et al. 2024. Cardiovasc Ther. 2024: 5583961. PMID: 38495810
- Adipose stem cells-derived small extracellular vesicles transport Thrombospondin 1 cargo to promote insulin resistance in gestational diabetes mellitus. | Li, H., et al. 2024. Diabetol Metab Syndr. 16: 105. PMID: 38764083
Inhibitor of:
ACRV1, BMP-6, dsg1α, GDF-9B, Inhibin β-E, LRRC70, LRRC72, MAWDBP1, Nodal, Ski, Smad1, Smad2, Smad4, Smad5, TBCK, TGF B3, TGF beta 1, TGF beta RI, TGFβ RIII, and TMEM100.Activator of:
CD109, and COL2A1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ITD 1, 10 mg | sc-507349 | 10 mg | $220.00 |