Isoxsuprine hydrochloride (CAS 579-56-6)
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Isoxsuprine hydrochloride is a smooth muscle relaxant. It acts by directly stimulating beta-adrenergic receptors, leading to an increase in intracellular cyclic AMP levels. This results in the relaxation of smooth muscles in the peripheral vasculature, particularly in the arteries and arterioles. By causing vasodilation, isoxsuprine hydrochloride can increase blood flow to certain tissues and organs. It may inhibit platelet aggregation, which may further contribute to its vasodilatory effects. At the molecular level, isoxsuprine hydrochloride exerts its action by binding to and activating beta-adrenergic receptors on smooth muscle cells, leading to the activation of adenylate cyclase and subsequent increase in cyclic AMP levels. This cascade of events ultimately leads to the relaxation of smooth muscle cells and vasodilation.
Isoxsuprine hydrochloride (CAS 579-56-6) References
- Effects of isoxsuprine hydrochloride on electrocardiographic and trace element status in sheeps. | Vural, HA., et al. 2016. J Pak Med Assoc. 66: 938-42. PMID: 27524523
- Exploring isoxsuprine hydrochloride binding with human serum albumin in the presence of folic acid and ascorbic acid using multispectroscopic and molecular modeling methods. | Shiri, F., et al. 2017. J Photochem Photobiol B. 170: 152-163. PMID: 28432945
- Comparative Study Between Zero-Order Spectra-Processing and Ratio Spectra-Manipulating Methods Applied for the Determination of Isoxsuprine Hydrochloride in the Presence of Its Oxidative Degradation Product. | Attia, KAM., et al. 2017. J AOAC Int. 100: 1739-1746. PMID: 28762327
- Binding Studies of Isoxsuprine Hydrochloride to Calf Thymus DNA Using Multispectroscopic and Molecular Docking Techniques. | Salehzadeh, S., et al. 2018. J Fluoresc. 28: 195-206. PMID: 28986738
- Binding interaction of isoxsuprine hydrochloride and levothyroxine to milk β-lactoglobulin; from the perspective of comparison. | Shahraki, S. and Shiri, F. 2018. Int J Biol Macromol. 109: 576-588. PMID: 29275203
- Effectiveness and Safety of Isoxsuprine Hydrochloride as Tocolytic Agent in Arresting Active/Threatened Preterm Labor and Its Role in Maintenance Tocolysis: A Prospective, Open-Label Study. | Jaju, PB. 2021. Am J Perinatol. 38: 291-295. PMID: 31550735
- Catalytic activity and structural changes of catalase in the presence of Levothyroxine and Isoxsuprine hydrochloride. | Shahraki, S., et al. 2020. Int J Biol Macromol. 152: 126-136. PMID: 32045611
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- Cardiac hypertrophy and insulin therapy in a pre-term newborn: is there a relationship? | Salvatori, G., et al. 2022. Ital J Pediatr. 48: 24. PMID: 35135591
- Fetal biometric and Doppler measurements following abdominal radical trachelectomy in the second trimester of the pregnancy. | Shima, E., et al. 2022. BMC Pregnancy Childbirth. 22: 343. PMID: 35443666
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- Laparoendoscopic single-site surgery for adnexal disease during pregnancy: A single-center preliminary experience. | Yin, M., et al. 2022. Front Surg. 9: 994360. PMID: 36311926
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Isoxsuprine hydrochloride, 5 g | sc-235434 | 5 g | $41.00 | |||
Isoxsuprine hydrochloride, 10 g | sc-235434A | 10 g | $88.00 |