Date published: 2026-5-13

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Isoxaflutole (CAS 141112-29-0)

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CAS Number:
141112-29-0
Molecular Weight:
359.32
Molecular Formula:
C15H12F3NO4S
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Isoxaflutole stands out as a pioneering pre-emergence herbicide, belonging to the isoxazole class. Specifically, it falls within the category of 1,2-oxazole, featuring substitutions at positions 4 and 5 – a 2-(methanesulfonyl)-4-(trifluoromethyl)benzoyl group and a cyclopropyl group, respectively. Notably, its functionality encompasses inhibition of 4-hydroxyphenylpyruvate dioxygenase, establishing its role as a vital contributor to the realm of herbicidal action.


Isoxaflutole (CAS 141112-29-0) References

  1. Soil metabolism of isoxaflutole in corn.  |  Rouchaud, J., et al. 2002. Arch Environ Contam Toxicol. 42: 280-5. PMID: 11910455
  2. Degradation of isoxaflutole (balance) herbicide by hypochlorite in tap water.  |  Lin, CH., et al. 2003. J Agric Food Chem. 51: 8011-4. PMID: 14690388
  3. Reaction pathways of the diketonitrile degradate of isoxaflutole with hypochlorite in water.  |  Lerch, RN., et al. 2007. J Agric Food Chem. 55: 1893-9. PMID: 17284050
  4. Improved HPLC-MS/MS method for determination of isoxaflutole (balance) and its metabolites in soils and forage plants.  |  Lin, CH., et al. 2007. J Agric Food Chem. 55: 3805-15. PMID: 17432871
  5. Processes affecting the dissipation of the herbicide isoxaflutole and its diketonitrile metabolite in agricultural soils under field conditions.  |  Papiernik, SK., et al. 2007. J Agric Food Chem. 55: 8630-9. PMID: 17880161
  6. Role of sorption and degradation in the herbicidal function of isoxaflutole.  |  Sims, GK., et al. 2009. Pest Manag Sci. 65: 805-10. PMID: 19333913
  7. Adsorption of isoxaflutole degradates to aluminum and iron hydrous oxides.  |  Wu, SH., et al. 2011. J Environ Qual. 40: 528-37. PMID: 21520760
  8. Comparison of transcriptome responses to glyphosate, isoxaflutole, quizalofop-p-ethyl and mesotrione in the HepaRG cell line.  |  Mesnage, R., et al. 2018. Toxicol Rep. 5: 819-826. PMID: 30128299
  9. Sensor-based evaluation of maize (Zea mays) and weed response to post-emergence herbicide applications of Isoxaflutole and Cyprosulfamide applied as crop seed treatment or herbicide mixing partner.  |  Mink, R., et al. 2020. Pest Manag Sci. 76: 1856-1865. PMID: 31828947
  10. Evaluation of data concerning the necessity of isoxaflutole as a herbicide to control a serious danger to plant health which cannot be contained by other available means, including non-chemical methods.  |  ,. 2017. EFSA J. 15: e04894. PMID: 32625535
  11. A field spray drift study to determine the downwind effects of isoxaflutole herbicide to nontarget plants.  |  Moore, DRJ., et al. 2022. Integr Environ Assess Manag. 18: 757-769. PMID: 34383375
  12. Simultaneous determination of isoxaflutole and its two metabolites in corn under field conditions by LC-MS/MS.  |  Lan, F., et al. 2022. J Sci Food Agric. 102: 3480-3486. PMID: 34820836
  13. A Multifunctional and Fast-Response Lysosome-Targetable Fluorescent Probe for Monitoring pH and Isoxaflutole.  |  Yang, L., et al. 2022. Int J Mol Sci. 23: PMID: 35682934
  14. Crystal structure, PIXEL calculations of inter-molecular inter-action energies and solid-state characterization of the herbicide isoxaflutole.  |  Schinke, J., et al. 2022. Acta Crystallogr E Crystallogr Commun. 78: 979-983. PMID: 36250109
  15. Production of Dichloroacetonitrile from Derivatives of Isoxaflutole Herbicide during Water Treatment.  |  Rogers, J., et al. 2023. Environ Sci Technol.. PMID: 36749696

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Isoxaflutole, 100 mg

sc-228380
100 mg
$119.00