Date published: 2026-5-22

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Isoxaben (CAS 82558-50-7)

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Application:
Isoxaben is a benzamide family herbicide that inhibits cellulose biosynthesis
CAS Number:
82558-50-7
Purity:
≥97%
Molecular Weight:
332.39
Molecular Formula:
C18H24N2O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Isoxaben, a benzamide class herbicide, is distinguished by its specific action mechanism targeting the biosynthesis of cellulose within plant cell walls, a critical process for plant structure and growth. By impeding cellulose production, Isoxaben effectively halts cell division during the mitotic phase, disrupting the normal development and regeneration of plants. This mode of action makes Isoxaben useful in agricultural and horticultural research, offering insights into cell wall biosynthesis pathways and the role of cellulose in plant morphology and stability.


Isoxaben (CAS 82558-50-7) References

  1. Modifications of cellulose synthase confer resistance to isoxaben and thiazolidinone herbicides in Arabidopsis Ixr1 mutants.  |  Scheible, WR., et al. 2001. Proc Natl Acad Sci U S A. 98: 10079-84. PMID: 11517344
  2. Degradation of isoxaben in soils and an aqueous system.  |  Camper, ND., et al. 2001. J Environ Sci Health B. 36: 729-39. PMID: 11757733
  3. Isolation and characterization of efficient isoxaben-transforming Microbacterium sp strains from four European soils.  |  Arrault, S., et al. 2002. Pest Manag Sci. 58: 1229-35. PMID: 12476996
  4. Fate of isoxaben in a containerized plant rhizosphere system.  |  Drakeford, CE., et al. 2003. Chemosphere. 50: 1243-7. PMID: 12547338
  5. Disruption of cellulose synthesis by isoxaben causes tip swelling and disorganizes cortical microtubules in elongating conifer pollen tubes.  |  Lazzaro, MD., et al. 2003. Protoplasma. 220: 201-7. PMID: 12664284
  6. Novel cell wall architecture of isoxaben-habituated Arabidopsis suspension-cultured cells: global transcript profiling and cellular analysis.  |  Manfield, IW., et al. 2004. Plant J. 40: 260-75. PMID: 15447652
  7. Isoxaben Inhibits the Synthesis of Acid Insoluble Cell Wall Materials In Arabidopsis thaliana.  |  Heim, DR., et al. 1990. Plant Physiol. 93: 695-700. PMID: 16667525
  8. Grass cell walls have a role in the inherent tolerance of grasses to the cellulose biosynthesis inhibitor isoxaben.  |  Brabham, C., et al. 2018. Pest Manag Sci. 74: 878-884. PMID: 29087620
  9. Alleles Causing Resistance to Isoxaben and Flupoxam Highlight the Significance of Transmembrane Domains for CESA Protein Function.  |  Shim, I., et al. 2018. Front Plant Sci. 9: 1152. PMID: 30197649
  10. Isoxaben analogs inhibit chitin synthesis in the cultured integument of the rice stem borer Chilo suppressalis.  |  Mori, K., et al. 2021. J Pestic Sci. 46: 120-123. PMID: 33746554
  11. The Cell Wall Proteome of Craterostigma plantagineum Cell Cultures Habituated to Dichlobenil and Isoxaben.  |  Guerriero, G., et al. 2021. Cells. 10: PMID: 34571944
  12. Review of the existing maximum residue levels for isoxaben according to Article 12 of Regulation (EC) No 396/2005.  |  , ., et al. 2022. EFSA J. 20: e07062. PMID: 35069885
  13. Isoxaben soil biodegradation in pear tree orchard after repeated high dose application.  |  Rouchaud, J., et al. 1997. Arch Environ Contam Toxicol. 33: 247-51. PMID: 9353201

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Isoxaben, 100 mg

sc-235431
100 mg
$60.00