Date published: 2026-2-22

1-800-457-3801

SCBT Portrait Logo
Seach Input

Isosorbide dimethyl ether (CAS 5306-85-4)

0.0(0)
Write a reviewAsk a question

Alternate Names:
2,5-Dimethylisosorbide
Application:
Isosorbide dimethyl ether is a speciality solvent
CAS Number:
5306-85-4
Purity:
≥97%
Molecular Weight:
174.19
Molecular Formula:
C8H14O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Isosorbide dimethyl ether is a derivative of isosorbide, characterized by the etherification of its hydroxyl groups with methyl groups, which significantly alters its physical and chemical properties for use in various scientific applications. This modification enhances the compound′s thermal stability and lipophilicity, making it particularly useful in materials science and polymer research. In these fields, isosorbide dimethyl ether is explored for its potential as a green solvent and as a monomer for synthesizing polymers with unique properties such as increased flexibility, durability, and lower environmental impact compared to traditional petroleum-based materials. Its application extends to the development of biodegradable plastics and elastomers, where its incorporation can improve the mechanical properties and decrease the carbon footprint of the final products. Moreover, the chemical′s non-toxicity and derived from renewable resources make it an attractive subject for sustainability studies focused on replacing hazardous solvents and materials in industrial processes. Research involving isosorbide dimethyl ether is driven by the goal to enhance the efficiency and eco-friendliness of material production processes, providing insights into the synthesis and application of bio-based chemicals in modern materials science.


Isosorbide dimethyl ether (CAS 5306-85-4) References

  1. Isosorbide as a renewable platform chemical for versatile applications--quo vadis?  |  Rose, M. and Palkovits, R. 2012. ChemSusChem. 5: 167-76. PMID: 22213713
  2. Preparation of polymeric particles in CO(2) medium using non-toxic solvents: formulation and comparisons with a phase separation method.  |  Tran, MK., et al. 2012. Eur J Pharm Biopharm. 82: 498-507. PMID: 22959993
  3. Sustained release of TGF-β1 from biodegradable microparticles prepared by a new green process in CO2 medium.  |  Swed, A., et al. 2015. Int J Pharm. 493: 357-65. PMID: 26209069
  4. Development of a non-toxic and non-denaturing formulation process for encapsulation of SDF-1α into PLGA/PEG-PLGA nanoparticles to achieve sustained release.  |  Haji Mansor, M., et al. 2018. Eur J Pharm Biopharm. 125: 38-50. PMID: 29325770
  5. Preparation of polymeric particles in CO2 medium using non-toxic solvents: discussions on the mechanism of particle formation.  |  Tran, MK., et al. 2015. J Mater Chem B. 3: 1573-1582. PMID: 32262429
  6. A study on the applicability of one-step vortex extraction and purification combined with gas chromatography-tandem mass spectrometry for analysis of four skin penetration enhancers in cosmetics.  |  Xiao, G., et al. 2023. J Chromatogr A. 1710: 464379. PMID: 37778099
  7. Novel cationically polymerizable propenyl and vinyl ethers derived from renewable sources  |  Crivello, J. V., & Bratslavsky, S. A. 1994. Journal of Polymer Science Part A: Polymer Chemistry. 32(15): 2919-2930.
  8. Heterogeneously catalysed production of isosorbide tert-butyl ethers  |  Rose, M., Thenert, K., Pfützenreuter, R., & Palkovits, R. 2013. Catalysis Science & Technology. 3(4): 938-941.
  9. Reaction network analysis and continuous production of isosorbide tert-butyl ethers  |  Pfützenreuter, R., Helmin, M., Palkovits, S., Palkovits, R., & Rose, M. 2014. Catalysis Today. 234: 113-118.
  10. Mitigating Cathodic Dissolution through Interfacial Water Masking to Enhance the Longevity of Aqueous Zinc-Ion Batteries  |  Zhong, W., Shen, Z., Mao, J., Zhang, S., Cheng, H., Kim, Y., & Lu, Y. 2024. Energy & Environmental Science. 17: 2059-2068.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Isosorbide dimethyl ether, 25 g

sc-250203
25 g
$59.00