Date published: 2025-11-14

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Isoquinoline-3-carboxylic acid (CAS 6624-49-3)

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CAS Number:
6624-49-3
Molecular Weight:
173.17
Molecular Formula:
C10H7NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Isoquinoline-3-carboxylic acid, referred to as IQ-3-COOH, is a naturally occurring organic compound that finds extensive use as a precursor in the synthesis of various compounds. This colorless and odorless crystalline solid demonstrates high solubility in both water and alcohol. Notably, it has been instrumental in generating pesticides and dyes. Moreover, Isoquinoline-3-carboxylic acid has contributed to the synthesis of polymers and other materials. The specific reaction mechanism of Isoquinoline-3-carboxylic acid heavily relies on various factors, such as the catalyst type, temperature, and pressure employed during the reaction. Generally, Isoquinoline-3-carboxylic acid acts as a nucleophilic compound and readily reacts with electrophiles like alkyl halides, aldehydes, and ketones. These reactions lead to the formation of a diverse array of products, including alcohols, amines, and carboxylic acids.


Isoquinoline-3-carboxylic acid (CAS 6624-49-3) References

  1. A class of novel N-isoquinoline-3-carbonyl-L-amino acid benzylesters: synthesis, anti-tumor evaluation and 3D QSAR analysis.  |  Zheng, M., et al. 2011. Eur J Med Chem. 46: 1672-81. PMID: 21414693
  2. Design, synthesis, and testing of an isoquinoline-3-carboxylic-based novel anti-tumor lead.  |  Gao, F., et al. 2015. Bioorg Med Chem Lett. 25: 4434-6. PMID: 26386603
  3. Cell cycle, apoptosis, cellular uptake and whole-transcriptome microarray gene expression analysis of HeLa cells treated with a ruthenium(II)-arene complex with an isoquinoline-3-carboxylic acid ligand.  |  Jovanović, KK., et al. 2016. J Inorg Biochem. 163: 362-373. PMID: 27118029

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Isoquinoline-3-carboxylic acid, 1 g

sc-263420
1 g
$60.00

Isoquinoline-3-carboxylic acid, 5 g

sc-263420A
5 g
$360.00