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Isophorone diisocyanate (CAS 4098-71-9)

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Alternate Names:
5-Isocyanato-1-(isocyanatomethyl)-1,3,3-trimethylcyclohexane
Application:
Isophorone diisocyanate is a chemical used in the production of polyurethanes
CAS Number:
4098-71-9
Purity:
≥97%
Molecular Weight:
222.28
Molecular Formula:
C12H18N2O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Isophorone diisocyanate may be used in the production of polyurethanes. Isophorone diisocyanate yields polyurethanes with high stability, discoloration and chemical resistant. Isophorone diisocyanate is a versatile compound that finds applications as a reagent in the synthesis of diverse compounds, including peptides, proteins, and nucleic acids. Furthermore, it serves as a valuable cross-linking agent in the formation of polymeric networks, providing enhanced structural integrity. Additionally, Isophorone diisocyanate plays a role in the synthesis of nanoparticles.


Isophorone diisocyanate (CAS 4098-71-9) References

  1. Diisocyanate emission from a paint product: a preliminary analysis.  |  Jarand, CW., et al. 2002. Appl Occup Environ Hyg. 17: 491-4. PMID: 12083169
  2. Chemical analysis of 2,4-toluene diisocyanate, 1,6-hexamethylene diisocyanate and isophorone diisocyanate in petrolatum patch-test preparations.  |  Frick-Engfeldt, M., et al. 2005. Dermatitis. 16: 130-5. PMID: 16242085
  3. Signalling pathway of isophorone diisocyanate-responsive interleukin-8 in airway smooth muscle cells.  |  Kuo, PL., et al. 2011. Eur Respir J. 37: 1226-36. PMID: 20817708
  4. Contact hypersensitivity response to isophorone diisocyanate in mice.  |  Stern, ML., et al. 1989. Drug Chem Toxicol. 12: 287-96. PMID: 2632247
  5. Site-Selective Modification of Cellulose Nanocrystals with Isophorone Diisocyanate and Formation of Polyurethane-CNC Composites.  |  Girouard, NM., et al. 2016. ACS Appl Mater Interfaces. 8: 1458-67. PMID: 26713564
  6. Fabrication of fluorescent carbon dots-linked isophorone diisocyanate and β-cyclodextrin for detection of chromium ions.  |  Wang, J., et al. 2017. Spectrochim Acta A Mol Biomol Spectrosc. 179: 163-170. PMID: 28242445
  7. Isophorone Diisocyanate: An Effective Additive to Form Cathode-Protective-Interlayer and Its Influence on LiNi0.5Co0.2Mn0.3O2 at High Potential.  |  Liu, Y., et al. 2018. ACS Appl Mater Interfaces. 10: 11305-11310. PMID: 29547257
  8. Effects of Isophorone Diisocyanate on the Thermal and Mechanical Properties of Shape-Memory Polyurethane Foams.  |  Hasan, SM., et al. 2014. Macromol Chem Phys. 215: 2420-2429. PMID: 30220825
  9. Isophorone Diisocyanate (IPDI) Microencapsulation for Mono-Component Adhesives: Effect of the Active H and NCO Sources.  |  Attaei, M., et al. 2018. Polymers (Basel). 10: PMID: 30960750
  10. Influence of the Prepolymer Type and Synthesis Parameters on Self-Healing Anticorrosion Properties of Composite Coatings Containing Isophorone Diisocyanate-Loaded Polyurethane Microcapsules.  |  Šobak, M., et al. 2021. Polymers (Basel). 13: PMID: 33803382
  11. Synthesis and Structure of 2-Hydroxypropyl Methacrylate-Capped Isophorone Diisocyanate and Poly(Propylene Glycol) Urethane Mixtures and the Properties of their UV-Cured Co-Networks with Isobornyl Methacrylate.  |  Zhou, J. and Tang, L. 2022. Materials (Basel). 15: PMID: 36500080
  12. Isophorone diisocyanate induced respiratory disease (IPDI).  |  Clarke, CW. and Aldons, PM. 1981. Aust N Z J Med. 11: 290-2. PMID: 6945844
  13. Biological monitoring of hexamethylene- and isophorone-diisocyanate by the determination of hexamethylene- and isophorone-diamine in hydrolysed urine using liquid chromatography and mass spectrometry.  |  Skarping, G., et al. 1994. Analyst. 119: 2051-5. PMID: 7978332
  14. Biocompatible polyurethane-based hydrogel.  |  Braatz, JA. 1994. J Biomater Appl. 9: 71-96. PMID: 7983587
  15. Test chamber exposure of humans to 1,6-hexamethylene diisocyanate and isophorone diisocyanate.  |  Tinnerberg, H., et al. 1995. Int Arch Occup Environ Health. 67: 367-74. PMID: 8567087

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Isophorone diisocyanate, 250 ml

sc-235411
250 ml
$88.00