Date published: 2026-4-5

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Isonicotinic acid (CAS 55-22-1)

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Alternate Names:
4-Pyridinecarboxylic acid
Application:
Isonicotinic acid is a useful isomer of nicotinic acid
CAS Number:
55-22-1
Molecular Weight:
123.11
Molecular Formula:
C6H5NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Isonicotinic acid is a compound that functions as a precursor in the synthesis of various agrochemicals. It acts as a building block for the production of pyridine derivatives, which are in the development of pesticides. At the molecular level, isonicotinic acid undergoes various chemical reactions to form key intermediates are for the synthesis of biologically active compounds. Its mechanism of action involves participating in organic synthesis reactions, leading to the formation of complex molecules with potential applications in the agricultural industries. Isonicotinic acid′s role in the production of pyridine derivatives contributes to the development of diverse chemical compounds with potential uses.


Isonicotinic acid (CAS 55-22-1) References

  1. Molecular ordering in isonicotinic acid on rutile TiO2(110) investigated with valence band photoemission.  |  O'Shea, JN., et al. 2004. J Chem Phys. 121: 10203-8. PMID: 15549895
  2. Infrared and Raman study of some isonicotinic acid metal(II) halide and tetracyanonickelate complexes.  |  Bardak, F., et al. 2009. Spectrochim Acta A Mol Biomol Spectrosc. 71: 1896-900. PMID: 18718809
  3. Induction of differentiation in k562 cell line by nicotinic acid-related compounds.  |  Ida, C., et al. 2009. Biosci Biotechnol Biochem. 73: 79-84. PMID: 19129652
  4. Two nd-zn and sm-zn isonicotinic/nicotinic Acid complexes.  |  Chen, WT. 2011. Acta Chim Slov. 58: 144-50. PMID: 24061955
  5. Synthesis, crystal structure and photoluminescence of a novel zinc-isonicotinic Acid complex.  |  Chen, WT. 2011. Acta Chim Slov. 58: 616-20. PMID: 24062126
  6. Theoretical Investigation of Tautomeric Equilibria for Isonicotinic Acid, 4-Pyridone, and Acetylacetone in Vacuo and in Solution.  |  Nagy, PI., et al. 2007. J Chem Theory Comput. 3: 1249-66. PMID: 26633199
  7. Structural Role of Isonicotinic Acid in U(VI), Np(VI), and Pu(VI) Complexes with TcO4-, ReO4-, and ClO4- Ions.  |  Budantseva, N., et al. 2017. Inorg Chem. 56: 12199-12205. PMID: 28949524
  8. New hydrazide-hydrazones of isonicotinic acid: synthesis, lipophilicity and in vitro antimicrobial screening.  |  Popiołek, Ł., et al. 2018. Chem Biol Drug Des. 91: 915-923. PMID: 29220872
  9. Significant improvement in conversion efficiency of isonicotinic acid by immobilization of cells via a novel microsphere preparation instrument.  |  Qian, J., et al. 2021. Bioresour Technol. 320: 124307. PMID: 33157446
  10. Isonicotinic acid N-oxide, from isoniazid biotransformation by Aspergillus niger, as an InhA inhibitor antituberculous agent against multiple and extensively resistant strains supported by in silico docking and ADME prediction.  |  Ragab, AE., et al. 2022. Nat Prod Res. 1-6. PMID: 35876096
  11. Impact of Isonicotinic Acid Blending in Chitosan/Polyvinyl Alcohol on Ripening-Dependent Changes of Green Stage Tomato.  |  Taher, MA. and Elsherbiny, EA. 2023. Polymers (Basel). 15: PMID: 36850109
  12. The determination of isoniazid and its metabolites acetylisoniazid, monoacetylhydrazine, diacetylhydrazine, isonicotinic acid and isonicotinylglycine in serum and urine.  |  Ellard, GA., et al. 1972. Biochem J. 126: 449-58. PMID: 5075259
  13. Niacin. II: Identification of isonicotinic acid in niacin by liquid chromatography with diode array detection.  |  Kirchhoefer, RD. 1994. J AOAC Int. 77: 587-90. PMID: 8012205
  14. Determination of isonicotinic acid in the presence of isoniazid and acetylisoniazid. Studies on isonicotinic acid formation from isoniazid in isolated rat hepatocytes.  |  Ono, Y., et al. 1996. J Chromatogr B Biomed Appl. 677: 339-43. PMID: 8704939
  15. Participation of P450-dependent oxidation of isoniazid in isonicotinic acid formation in rat liver.  |  Ono, Y., et al. 1998. Biol Pharm Bull. 21: 421-5. PMID: 9586587

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Isonicotinic acid, 100 g

sc-250188
100 g
$32.00

Isonicotinic acid, 1 kg

sc-250188A
1 kg
$146.00

Isonicotinic acid, 2.5 kg

sc-250188B
2.5 kg
$333.00

Isonicotinic acid, 5 kg

sc-250188C
5 kg
$624.00