Molecular structure of Isoguanine, CAS Number: 3373-53-3
Isoguanine (CAS 3373-53-3)
Alternate Names:
6-Amino-1,3-dihydro-2H-purin-2-one
Application:
Isoguanine is A nucleotide base as immunostimulator agent
CAS Number:
3373-53-3
Purity:
≥95%
Molecular Weight:
151.13
Molecular Formula:
C5H5N5O
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Isoguanine functions as a structural analog of guanine in nucleic acids. It can pair with cytosine during DNA replication and transcription, leading to potential mutagenic effects. Isoguanine can also be used to study the impact of guanine analogs on DNA stability and replication fidelity. At the molecular level, isoguanine can disrupt the normal base pairing interactions in DNA, leading to altered genetic information. Its mechanism of action involves interfering with the normal hydrogen bonding patterns in DNA, leading to potential errors in DNA replication and transcription processes. Isoguanine′s role in experimental applications involves providing insights into the impact of guanine analogs on DNA structure and function.
Isoguanine (CAS 3373-53-3) References
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- Molecular tapes in the structure of isoguaninium chloride. | Budniak, UA. and Dominiak, PM. 2018. Acta Crystallogr C Struct Chem. 74: 108-112. PMID: 29303504
- Identification and quantification of isoguanosine in humans and mice. | Weimann, A., et al. 2019. Scand J Clin Lab Invest. 79: 225-232. PMID: 30888208
- Fused Heterocyclic Systems with an s-Triazine Ring. 34. Development of a Practical Approach for the Synthesis of 5-Aza-isoguanines. | Junaid, A., et al. 2019. Molecules. 24: PMID: 31013786
- Photodynamics of alternative DNA base isoguanine. | Gate, G., et al. 2019. Phys Chem Chem Phys. 21: 13474-13485. PMID: 31204732
- Could Purines Be Formed from Cyanamide and Cyanoacetylene in a Prebiotic Earth Environment? | Kaur, S., et al. 2019. ACS Omega. 4: 12771-12781. PMID: 31460401
- Fluorescence of the tri-cyclic adenine and isoguanine derivatives and their ribosides: possible analytical applications. | Stachelska-Wierzchowska, A. and Wierzchowski, J. 2019. Acta Biochim Pol. 66: 585-588. PMID: 31804790
- Accurate geometrical restraints for Watson-Crick base pairs. | Gilski, M., et al. 2019. Acta Crystallogr B Struct Sci Cryst Eng Mater. 75: 235-245. PMID: 32830749
- Chemically Stabilized DNA Barcodes for DNA-Encoded Chemistry. | Potowski, M., et al. 2021. Angew Chem Int Ed Engl. 60: 19744-19749. PMID: 34153170
- Identifying the wide diversity of extraterrestrial purine and pyrimidine nucleobases in carbonaceous meteorites. | Oba, Y., et al. 2022. Nat Commun. 13: 2008. PMID: 35473908
- A novel chromatin regulator-related immune checkpoint related gene prognostic signature and potential candidate drugs for endometrial cancer patients. | Liu, Z., et al. 2022. Hereditas. 159: 40. PMID: 36253800
- Integrated metabolomic and transcriptomic analysis reveals the role of phenylpropanoid biosynthesis pathway in tomato roots during salt stress. | Jia, C., et al. 2022. Front Plant Sci. 13: 1023696. PMID: 36570882
- The Base Pairs of Isoguanine and 8-Aza-7-deazaisoguanine with 5-Methylisocytosine as Targets for DNA Functionalization. | Kondhare, D., et al. 2023. Bioconjug Chem. 34: 422-432. PMID: 36735859
- A bioinformatics approach to identifying the biomarkers and pathogenesis of major depressive disorder combined with acute myocardial infarction. | Yu, C., et al. 2023. Am J Transl Res. 15: 932-948. PMID: 36915729
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Isoguanine, 100 mg | sc-211670 | 100 mg | $206.00 |