Date published: 2026-4-26

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Isofenphos-methyl (CAS 99675-03-3)

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Alternate Names:
Isopropyl 2-{[(isopropylamino)(methoxy)phosphorothioyl]oxy}benzoate
CAS Number:
99675-03-3
Purity:
≥95%
Molecular Weight:
331.37
Molecular Formula:
C14H22NO4PS
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Isofenphos-methyl, a compound extensively researched in scientific studies, serves as a valuable model for examining the mechanism of action in organophosphate insecticides and acaricides. Moreover, it aids in the investigation of the biochemical impacts associated with organophosphates. Isofenphos-methyl operates by inhibiting the function of acetylcholinesterase, a vital enzyme responsible for nerve transmission in insects and mites. This inhibition results in the buildup of acetylcholine.


Isofenphos-methyl (CAS 99675-03-3) References

  1. Determination of selected non-authorized insecticides in peppers by liquid chromatography time-of-flight mass spectrometry and tandem mass spectrometry.  |  Mezcua, M., et al. 2008. Rapid Commun Mass Spectrom. 22: 1384-92. PMID: 18381615
  2. Desorption electrospray ionization mass spectrometry for trace analysis of agrochemicals in food.  |  García-Reyes, JF., et al. 2009. Anal Chem. 81: 820-9. PMID: 19090743
  3. Isolation of an isocarbophos-degrading strain of Arthrobacter sp. scl-2 and identification of the degradation pathway.  |  Rong, L., et al. 2009. J Microbiol Biotechnol. 19: 1439-46. PMID: 19996699
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  5. Screening of agrochemicals in foodstuffs using low-temperature plasma (LTP) ambient ionization mass spectrometry.  |  Wiley, JS., et al. 2010. Analyst. 135: 971-9. PMID: 20419245
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  7. Multi-residue analysis of pesticides in traditional Chinese medicines using gas chromatography-negative chemical ionisation tandem mass spectrometry.  |  Nie, J., et al. 2015. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 32: 1287-300. PMID: 26125677
  8. Enantioseparation and determination of isofenphos-methyl enantiomers in wheat, corn, peanut and soil with Supercritical fluid chromatography/tandem mass spectrometric method.  |  Chen, X., et al. 2016. J Chromatogr B Analyt Technol Biomed Life Sci. 1015-1016: 13-21. PMID: 26894851
  9. Enantiomeric separation of six chiral pesticides that contain chiral sulfur/phosphorus atoms by supercritical fluid chromatography.  |  Zhang, L., et al. 2018. J Sep Sci. 41: 1460-1470. PMID: 29337424
  10. Enantioselective analysis and degradation of isofenphos-methyl in vegetables by liquid chromatography-tandem mass spectrometry.  |  Wang, L., et al. 2018. Environ Sci Pollut Res Int. 25: 18772-18780. PMID: 29713973
  11. A potential biomarker of isofenphos-methyl in humans: A chiral view.  |  Gao, B., et al. 2019. Environ Int. 127: 694-703. PMID: 30991225
  12. Enantioselective disposition and metabolic products of isofenphos-methyl in rats and the hepatotoxic effects.  |  Gao, B., et al. 2020. Environ Int. 143: 105940. PMID: 32663714
  13. Human health risk assessment of pesticide residues in honeysuckle samples from different planting bases in China.  |  Wu, P., et al. 2021. Sci Total Environ. 759: 142747. PMID: 33121779
  14. Enantioselective degradation of the organophosphorus insecticide isocarbophos in Cupriavidus nantongensis X1T: Characteristics, enantioselective regulation, degradation pathways, and toxicity assessment.  |  Fang, L., et al. 2021. J Hazard Mater. 417: 126024. PMID: 33992014
  15. Detection and Risk Assessments of Multi-Pesticides in Traditional Chinese Medicine Chuanxiong Rhizoma by LC/MS-MS and GC/MS-MS.  |  Zhang, D., et al. 2022. Molecules. 27: PMID: 35163887
  16. Screening of multiclass pesticide residues in maca and Moringa oleifera by a modified QuEChERS sample preparation procedure and UPLC-ESI-MS/MS analysis.  |  Zhu, Y., et al. 2020. RSC Adv. 10: 36906-36919. PMID: 35517969
  17. Toxic effects of isofenphos-methyl on zebrafish embryonic development.  |  Wu, Y., et al. 2023. Ecotoxicol Environ Saf. 254: 114723. PMID: 36871354

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Isofenphos-methyl, 50 mg

sc-228369
50 mg
$219.00