Date published: 2025-10-19

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(isobutyrylamino)acetic acid (CAS 15926-18-8)

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Alternate Names:
N-(2-methylpropanoyl)glycine
CAS Number:
15926-18-8
Molecular Weight:
145.16
Molecular Formula:
C6H11NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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(Isobutyrylamino)acetic acid is a chemical compound integrating an isobutyric acid moiety with a glycine derivative, characterized by an isobutyryl group linked to the nitrogen of glycine through an amide bond. This structure lends the molecule unique properties that make it valuable in synthetic chemistry, particularly in peptide synthesis where it′s used to introduce isobutyryl groups into peptides. These modifications can significantly alter peptide properties such as stability, hydrophobicity, and membrane interactions, making (isobutyrylamino)acetic acid crucial for studying peptide behavior and functionality. In research, this compound has been employed extensively to explore protein and peptide structure-function relationships, aiding in the development of novel peptides with tailored biological activities. Its ability to affect protein interactions and stability through acylation makes it a useful tool in protein engineering and in the broader field of biochemistry, where understanding and manipulating peptide and protein dynamics are key to advancements.


(isobutyrylamino)acetic acid (CAS 15926-18-8) References

  1. Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.  |  Goldsborough, AS., et al. 2011. J Med Chem. 54: 4987-97. PMID: 21657271

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

(isobutyrylamino)acetic acid, 1 g

sc-351798
1 g
$300.00

(isobutyrylamino)acetic acid, 5 g

sc-351798A
5 g
$1163.00