Date published: 2025-10-3

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Isoacteoside (CAS 61303-13-7)

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Application:
Isoacteoside is a glycoside
CAS Number:
61303-13-7
Purity:
≥97%
Molecular Weight:
624.59
Molecular Formula:
C29H36O15
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Isoacteoside is a phenolic glycoside compound that occurs naturally in various plants, including Verbascum thapsus, Verbascum phlomoides, and Verbascum densiflorum. This compound has a long history of use in traditional medicine and is renowned for its anti-inflammatory, antioxidant, and antimicrobial properties. In vitro studies have primarily examined the impact of isoverbascoside on cell cultures. These investigations have revealed that isoverbascoside possesses the ability to induce apoptosis in cancer cells, impede the growth of specific viruses, and modulate the expression of specific genes.


Isoacteoside (CAS 61303-13-7) References

  1. Antioxidant principles from Bauhinia tarapotensis.  |  Braca, A., et al. 2001. J Nat Prod. 64: 892-5. PMID: 11473417
  2. Antiproliferative constituents in the plants 7. Leaves of Clerodendron bungei and leaves and bark of C. trichotomum.  |  Nagao, T., et al. 2001. Biol Pharm Bull. 24: 1338-41. PMID: 11725977
  3. Isolation and purification of acteoside and isoacteoside from Plantago psyllium L. by high-speed counter-current chromatography.  |  Li, L., et al. 2005. J Chromatogr A. 1063: 161-9. PMID: 15700468
  4. Biosynthesis of acteoside in cultured cells of Olea europaea.  |  Saimaru, H. and Orihara, Y. 2010. J Nat Med. 64: 139-45. PMID: 20037799
  5. Phenylpropanoids from the stem bark of Jacaranda mimosaefolia.  |  Zaghloul, AM., et al. 2011. Nat Prod Res. 25: 68-76. PMID: 21240764
  6. Two-phase hollow fiber liquid phase microextraction based on magnetofluid for simultaneous determination of Echinacoside, Tubuloside B, Acteoside and Isoacteoside in rat plasma after oral administration of Cistanche salsa extract by high performance liquid chromatography.  |  Zhou, J., et al. 2014. J Pharm Biomed Anal. 94: 30-5. PMID: 24531006
  7. Anti-inflammatory effects of isoacteoside from Abeliophyllum distichum.  |  Nam, SY., et al. 2015. Immunopharmacol Immunotoxicol. 37: 258-64. PMID: 25975581
  8. A metabolic way to investigate related hurdles causing poor bioavailability in oral delivery of isoacteoside in rats employing ultrahigh-performance liquid chromatography/quadrupole time-of-flight tandem mass spectrometry.  |  Cui, Q., et al. 2017. Rapid Commun Mass Spectrom. 31: 371-380. PMID: 27859774
  9. Isoacteoside, a dihydroxyphenylethyl glycoside, exhibits anti-inflammatory effects through blocking toll-like receptor 4 dimerization.  |  Gao, H., et al. 2017. Br J Pharmacol. 174: 2880-2896. PMID: 28616865
  10. Medicinal plants with concomitant anti-diabetic and anti-hypertensive effects as potential sources of dual acting therapies against diabetes and hypertension: A review.  |  Chukwuma, CI., et al. 2019. J Ethnopharmacol. 235: 329-360. PMID: 30769039
  11. Suppression of in vitro and in vivo human ovarian cancer growth by isoacteoside is mediated via sub-G1 cell cycle arrest, ROS generation, and modulation of AKT/PI3K/m-TOR signalling pathway.  |  Yang, X., et al. 2019. J BUON. 24: 285-290. PMID: 30941982
  12. Enzyme inhibitory assessment of the isolated constituents from Plantago holosteum Scop.  |  Guragac Dereli, FT., et al. 2020. Z Naturforsch C J Biosci. 75: 121-128. PMID: 32267249
  13. Identification and quantification of the bioactive components in Osmanthus fragrans roots by HPLC-MS/MS.  |  Liao, X., et al. 2021. J Pharm Anal. 11: 299-307. PMID: 34277118
  14. Isolation of Some Phenolic Compounds from Plantago subulata L. and Determination of Their Antidiabetic, Anticholinesterase, Antiepileptic and Antioxidant Activity.  |  Özaslan, MS., et al. 2022. Chem Biodivers. 19: e202200280. PMID: 35796520

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Isoacteoside, 10 mg

sc-286020
10 mg
$312.00

Isoacteoside, 25 mg

sc-286020A
25 mg
$618.00