(+)-Irinotecan (CAS 97682-44-5)
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(+)-Irinotecan is a compound studied in the field of chemical biology for its interactions with cellular enzymes. In biochemistry, it serves to investigate the mechanisms of action of topoisomerase inhibitors. By studying (+)-Irinotecan, researchers gain insights into the enzyme kinetics and the molecular pathways that govern DNA replication and transcription. The compound is also in studies focusing on cellular responses to DNA damage, such as cell cycle arrest and apoptosis. (+)-Irinotecan′s role in the modification of gene expression is of interest in the field of molecular genetics. (+)-Irinotecan contributes to the broader scientific understanding of DNA dynamics and the cellular machinery involved in maintaining genomic integrity.
(+)-Irinotecan (CAS 97682-44-5) References
- Allometric scaling of a metabolically complex camptothecin analog: differences in scaling of irinotecan and its active metabolite, SN-38. | Ahlawat, P. and Srinivas, NR. 2009. Arzneimittelforschung. 59: 311-7. PMID: 19634513
- Blue light emitting diodes irradiation causes cell death in colorectal cancer by inducing ROS production and DNA damage. | Yan, G., et al. 2018. Int J Biochem Cell Biol. 103: 81-88. PMID: 30125666
- Transmissible Gastroenteritis Virus Nucleocapsid Protein Interacts with Na+/H+ Exchanger 3 To Reduce Na+/H+ Exchanger Activity and Promote Piglet Diarrhea. | Niu, Z., et al. 2022. J Virol. 96: e0147322. PMID: 36342433
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
(+)-Irinotecan, 10 mg | sc-269253 | 10 mg | $61.00 |