Molecular structure of Ipratropium bromide, CAS Number: 22254-24-6
Ipratropium bromide (CAS 22254-24-6)
See product citations (3)
Alternate Names:
(endo,syn)-(±)-3-(3-Hydroxy-1-oxo-2-phenylpropoxy)-8-methyl-8-(1-methylethyl)-8-azoniabicyclo[3.2.1]octane bromide
Application:
Ipratropium bromide is an N-isopropyl salt of atropine and muscarinic antagonist
CAS Number:
22254-24-6
Purity:
≥98%
Molecular Weight:
412.37
Molecular Formula:
C20H30BrNO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ipratropium bromide is a compound extensively used in research focused on respiratory system function and autonomic nervous system regulation. It acts as an antagonist of muscarinic acetylcholine receptors, which are distributed throughout the bronchial tree. Studies involving Ipratropium bromide contribute to the understanding of bronchodilation mechanisms and airway resistance. It is also used in the investigation of cholinergic signaling pathways and their role in respiratory physiology. Research on Ipratropium bromide has a significant impact on the development of novel strategies for studying and managing conditions that affect breathing and airway constriction.
Ipratropium bromide (CAS 22254-24-6) References
- Effect of ipratropium bromide in bronchial asthma. | Taskar, V., et al. 1992. J Postgrad Med. 38: 124-6. PMID: 1303412
- Cardiovascular events associated with ipratropium bromide in COPD. | Ogale, SS., et al. 2010. Chest. 137: 13-9. PMID: 19363211
- Computational and vibrational spectroscopic studies of ipratropium bromide. | Ali, HR., et al. 2009. Drug Test Anal. 1: 73-80. PMID: 20355179
- Bronchodilator responses to salbutamol followed by ipratropium bromide in partially reversible airflow obstruction. | Barros, MJ. and Rees, PJ. 1990. Respir Med. 84: 371-5. PMID: 2147295
- Stimulation of suicidal erythrocyte death by ipratropium bromide. | Shaik, N., et al. 2012. Cell Physiol Biochem. 30: 1517-25. PMID: 23235556
- Transient anisocoria in a patient treated with nebulized ipratropium bromide. | Pejic, R. and Klaric, B. 2017. Am J Ophthalmol Case Rep. 7: 11-13. PMID: 29260071
- Pharmacologic anisocoria due to nebulized ipratropium bromide: A diagnostic challenge. | Kokulu, K., et al. 2019. Am J Emerg Med. 37: 1217.e3-1217.e4. PMID: 30948255
- Effects of ipratropium bromide on the occurrence of postoperative respiratory complications in craniectomy patients with COPD: A nationwide multicenter retrospective study. | Du, Z., et al. 2020. Medicine (Baltimore). 99: e20836. PMID: 32590774
- Calculating the Charcoal Blockade Efficiency for Bioequivalence Study of Inhaled Ipratropium Bromide Using A Model Method. | Cheng, Y., et al. 2022. J Pharm Sci. 111: 2107-2115. PMID: 35257696
- Ipratropium bromide and noninvasive ventilation treatment for COPD. | Lin, S., et al. 2022. Am J Transl Res. 14: 3319-3326. PMID: 35702113
- Compound Ipratropium Bromide plus Budesonide Inhalation in the Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease and Its Effect on Heparin-Binding Protein. | Dong, Y. and Li, Q. 2022. Evid Based Complement Alternat Med. 2022: 4457740. PMID: 35832532
- The Effect of Ipratropium Bromide with Violet Flower Extract, Ipratropium Bromide with Budesonide, and Ipratropium Bromide Alone on the Cuff-Leak of the Endotracheal Tube in Intubated ICU Patients. | Hashemi, ST., et al. 2023. Adv Biomed Res. 12: 74. PMID: 37200760
- Dose-response comparison of ipratropium bromide from a metered-dose inhaler and by jet nebulisation. | Gomm, SA., et al. 1983. Thorax. 38: 297-301. PMID: 6223402
- The separation of ipratropium bromide and its related compounds. | Simms, PJ., et al. 1998. J Pharm Biomed Anal. 17: 841-9. PMID: 9682169
Inhibitor of:
E3BP, mAChR M, mAChR M1, mAChR M2, mAChR M3, mAChR M4, Olfr1039, Olfr1100, Olfr639, Olr1514, Olr27, RSHL3, Siglec-8, and SMGC.Activator of:
Basal ciliated, and CLCA1_Clac1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ipratropium bromide, 100 mg | sc-203606 | 100 mg | $85.00 |