Molecular structure of Iohexol-d5, CAS Number: 928623-33-0
Iohexol-d5 (CAS 928623-33-0)
See product citations (2)
Alternate Names:
Iohexol-d5 is also known as Nycodenz-d5.
Application:
Iohexol-d5 is a non-ionic and water-soluble contrast agent used as a reference marker to determine the glomerular filtration rate with minimal neurotoxicity.
CAS Number:
928623-33-0
Molecular Weight:
826.17
Molecular Formula:
C19H21D5I3N3O9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Iohexol-d5 is a deuterated compound often utilized in analytical chemistry and environmental research. It is used as an internal standard for quantifying iohexol through mass spectrometry due to the deuterium atoms that provide a distinct mass difference, enabling more accurate and sensitive measurement. In environmental studies, iohexol-d5 helps in tracing the presence and assessing the fate of contrast agents in water systems, contributing to the understanding of pharmaceutical pollutants. The compound also plays a role in the calibration of analytical instruments, ensuring that the measurements of iohexol in complex biological or environmental samples are precise and reliable. Researchers value iohexol-d5 for its ability to improve method development in the quantification of small organic molecules in various matrices.
Iohexol-d5 (CAS 928623-33-0) References
- Validation of a routine two-sample iohexol plasma clearance assessment of GFR and an evaluation of common endogenous markers in a rat model of CKD. | Turner, ME., et al. 2017. Physiol Rep. 5: PMID: 28483858
- Advances and perspectives in tissue clearing using CLARITY. | Jensen, KHR. and Berg, RW. 2017. J Chem Neuroanat. 86: 19-34. PMID: 28728966
- Effects of iopentol, iohexol and metrizoate on the contractility of the isolated rabbit heart. | Almén, T. and Bååth, L. 1987. Acta Radiol Suppl. 370: 61-3. PMID: 2980314
- Verification of separate measurement procedures where analytical determinations influence the clinical interpretation of GFR: Iohexol quantitation by HPLC and LC-MS/MS. | Schmit, DJ., et al. 2019. Clin Biochem. 67: 16-23. PMID: 30905584
- Development and validation of an ultra-high performance liquid chromatography-tandem mass spectrometry method for the simultaneous determination of iohexol, p-aminohippuric acid and creatinine in porcine and broiler chicken plasma. | Dhondt, L., et al. 2019. J Chromatogr B Analyt Technol Biomed Life Sci. 1117: 77-85. PMID: 31004849
- A direct injection liquid chromatography tandem mass spectrometry method for the kinetic study on iodinated contrast media (ICMs) removal in natural water. | Lopez-Prieto, IJ., et al. 2020. Chemosphere. 243: 125311. PMID: 31759215
- Volumetric absorptive microsampling as alternative sampling technique for renal function assessment in the paediatric population using iohexol. | Dhondt, L., et al. 2021. J Chromatogr B Analyt Technol Biomed Life Sci. 1171: 122623. PMID: 33735803
- Occurrence and risk of iodinated X-ray contrast media in source and tap water from Jiangsu province, China. | Cheng, X., et al. 2023. J Hazard Mater. 444: 130399. PMID: 36403453
- Iohexol-measured glomerular filtration rate and urinary biomarker changes between vancomycin and vancomycin plus piperacillin-tazobactam in a translational rat model. | Chang, J., et al. 2023. bioRxiv.. PMID: 36945555
- Comparative trial of iohexol 350, a non-ionic contrast medium, with diatrizoate (Urografin 370) in left ventriculography and coronary arteriography. | Sullivan, ID., et al. 1984. Br Heart J. 51: 643-7. PMID: 6375703
- Contrast agents for cardiac angiography: effects of a nonionic agent vs. a standard ionic agent. | Bettmann, MA., et al. 1984. Radiology. 153: 583-7. PMID: 6387783
- Hemodynamic and electrocardiographic effects in man of a new nonionic contrast agent (iohexol): advantages over standard ionic agents. | Mancini, GB., et al. 1983. Am J Cardiol. 51: 1218-22. PMID: 6837464
- Neurotoxicity of iohexol: a new nonionic contrast medium. | Bryan, RN., et al. 1982. Radiology. 145: 379-82. PMID: 7134441
- New angiographic agents with less fibrillatory propensity. | Wolf, GL., et al. 1981. Invest Radiol. 16: 320-3. PMID: 7275545
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Iohexol-d5, 1 mg | sc-280838 | 1 mg | $745.00 | |||
Iohexol-d5, 10 mg | sc-280838A | 10 mg | $3742.00 |