Molecular structure of Iohexol, CAS Number: 66108-95-0
Iohexol (CAS 66108-95-0)
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Alternate Names:
Iohexol is also known as Win-39424.
Application:
Iohexol is a nonionic and water-soluble contrast agent that can induce inhibition of electrical activity.
CAS Number:
66108-95-0
Purity:
≥98%
Molecular Weight:
821.14
Molecular Formula:
C19H26I3N3O9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Iohexol is a nonionic and water-soluble contrast agent that can induce inhibition of electrical activity. Minimal neurotoxicity was indicated both in vitro and invivo when Iohexol was used to induce inhibition of electrical activity in rat and feline specimens. Compared to metrizoate, Iohexol induced a smaller decrease in contractile force in isolated rabbit hearts. Iohexol may also be used in the imaging and visualization of arteries, veins, joints, and the urinary tract.
Iohexol (CAS 66108-95-0) References
- The iodinated radiographic contrast medium iohexol mimics the vasodilator effect seen with small increases in extracellular K+ in the isolated rabbit central ear artery. | Frønes, S., et al. 2006. Acta Radiol. 47: 692-8. PMID: 16950707
- Estimation of intestinal permeability in healthy dogs using the contrast medium iohexol. | Klenner, S., et al. 2009. Vet Clin Pathol. 38: 353-60. PMID: 19351334
- Iontophoretic transdermal sampling of iohexol as a non-invasive tool to assess glomerular filtration rate. | Djabri, A., et al. 2015. Pharm Res. 32: 590-603. PMID: 25190007
- Iohexol plasma clearance in children: validation of multiple formulas and two-point sampling times. | Tøndel, C., et al. 2017. Pediatr Nephrol. 32: 311-320. PMID: 27369694
- A Simple Method to Measure Renal Function in Swine by the Plasma Clearance of Iohexol. | Luis-Lima, S., et al. 2018. Int J Mol Sci. 19: PMID: 29329247
- Excretion of iohexol and metrizoate in human breast milk. | Nielsen, ST., et al. 1987. Acta Radiol. 28: 523-6. PMID: 2960342
- Control of optical transparency and infrared laser heating of costal cartilage via injection of iohexol. | Alexandrovskaya, YM., et al. 2018. J Biophotonics. 11: e201800195. PMID: 30043483
- Verification of separate measurement procedures where analytical determinations influence the clinical interpretation of GFR: Iohexol quantitation by HPLC and LC-MS/MS. | Schmit, DJ., et al. 2019. Clin Biochem. 67: 16-23. PMID: 30905584
- Accuracy of determination of the glomerular filtration marker iohexol by European laboratories as monitored by external quality assessment. | Nordin, G., et al. 2019. Clin Chem Lab Med. 57: 1006-1011. PMID: 31075079
- Enhanced specificity due to method specific limits for relative ion intensities in a high-performance liquid chromatography - tandem mass spectrometry method for iohexol in human serum. | Schweinsberg, V., et al. 2020. Clin Chem Lab Med. 58: 709-718. PMID: 32069224
- Iohexol assay for direct determination of glomerular filtration rate: optimization and development of an HPLC-UV method for measurement in serum and urine. | El Assri, S., et al. 2020. Clin Chim Acta. 508: 115-121. PMID: 32416172
- Iohexol inhibits adenylate cyclase. | Harnish, PP., et al. 1988. Invest Radiol. 23: 139-42. PMID: 3343111
- Plasma clearance of nonradioactive iohexol as a measure of glomerular filtration rate. | Gaspari, F., et al. 1995. J Am Soc Nephrol. 6: 257-63. PMID: 7579093
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Iohexol, 1 g | sc-205351 | 1 g | $54.00 | |||
Iohexol, 5 g | sc-205351A | 5 g | $104.00 | |||
Iohexol, 25 g | sc-205351B | 25 g | $214.00 |