Date published: 2026-4-5

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Iodoform (CAS 75-47-8)

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Alternate Names:
Triiodomethane
CAS Number:
75-47-8
Molecular Weight:
393.73
Molecular Formula:
CHI3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Iodoform is used as a reagent in organic synthesis. It functions as a source of iodine in various chemical reactions, particularly in the preparation of certain organic compounds. When iodoform is used in a reaction, it undergoes a series of chemical transformations, ultimately leading to the incorporation of iodine into the target molecule. This process involves the release of iodine atoms from the iodoform molecule, which then react with other compounds to form new chemical bonds. The mechanism of action of iodoform involves its ability to serve as a convenient and effective source of iodine atoms for use in a variety of synthetic transformations. Its reactivity and selectivity make it useful for introducing iodine-containing functional groups into organic molecules, enabling the synthesis of diverse chemical compounds for research and development purposes.


Iodoform (CAS 75-47-8) References

  1. [Iodoform poisoning. 3 cases].  |  Harry, P., et al. 1992. J Toxicol Clin Exp. 12: 35-42. PMID: 1460590
  2. Photochemistry of iodoform in methanol: formation and fate of the iso-CHI2-I photoproduct.  |  El-Khoury, PZ., et al. 2009. Chemphyschem. 10: 1895-900. PMID: 19373794
  3. Iodoform gauze removes necrotic tissue from pressure ulcer wounds by fibrinolytic activity.  |  Mizokami, F., et al. 2012. Biol Pharm Bull. 35: 1048-53. PMID: 22791151
  4. The impact of the addition of iodoform on the physicochemical properties of an epoxy-based endodontic sealer.  |  Kuga, MC., et al. 2014. J Appl Oral Sci. 22: 125-30. PMID: 24676583
  5. Hydractinia echinata test-system. IV. Toxic synergism of human pharmaceuticals in mixtures with iodoform.  |  Chicu, SA., et al. 2016. Ecotoxicol Environ Saf. 134P1: 80-85. PMID: 27591706
  6. Small trial shows high rates of endodontic treatment success with iodoform or calcium hydroxide paste in primary teeth after 1 year.  |  Brignardello-Petersen, R. 2019. J Am Dent Assoc. 150: e122. PMID: 31174815
  7. Iodoform and silver-coated abutments preventing bacterial leakage through the implant-abutment interfaces: In vitro analysis using molecular-based method.  |  do Nascimento, C., et al. 2019. Arch Oral Biol. 105: 65-71. PMID: 31276940
  8. Synthesis of Micrometer-Sized Poly(methyl acrylate) by Temperature-Step Microsuspension Polymerization with Iodoform Based on the 'Radical Exit Depression' Effect§.  |  Huang, C., et al. 2021. Langmuir. 37: 3158-3165. PMID: 33667340
  9. Outcomes of Calcium Hydroxide with Iodoform Pulpectomies in Primary Teeth.  |  Matalon, V., et al. 2021. J Dent Child (Chic). 88: 46-51. PMID: 33875052
  10. Wound Antiseptics and European Guidelines for Antiseptic Application in Wound Treatment.  |  Babalska, ZŁ., et al. 2021. Pharmaceuticals (Basel). 14: PMID: 34959654
  11. Visible-Light-Mediated Three-Component Radical Iodosulfonylative Cyclization of Enynes.  |  Cheng, Q., et al. 2022. Org Lett. 24: 2515-2519. PMID: 35352951
  12. Iodoform as a Dressing, Especially in Tubercular Ulcerations of Bones and Joints.  |  Mikulicz,. and Peterson, F. 1881. Buffalo Med Surg J. 20: 552-554. PMID: 36667407
  13. Role of iodoform in jaw lesions: a systematic review.  |  Arangaraju, R., et al. 2023. Br J Oral Maxillofac Surg. 61: 385-393. PMID: 37271603

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Iodoform, 5 g

sc-250162
5 g
$31.00