Molecular structure of Iodoacetic acid, CAS Number: 64-69-7
Iodoacetic acid (CAS 64-69-7)
Application:
Iodoacetic acid is a reagent useful for modifying cysteine residues
CAS Number:
64-69-7
Molecular Weight:
185.95
Molecular Formula:
C2H3IO2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Iodoacetic acid is a reagent for the modification and alkylation of cysteine residues in proteins. It has also been used in glycopeptide synthesis. Iodoacetic acid is a compound found in colorless or white crystal form. It belongs to the haloacetic acid family and is derived from acetic acid by replacing one of the hydrogens in the methyl group with an iodine atom. This substitution gives it the properties of an alkylating agent. Iodoacetic acid is classified as an organoiodine compound and a haloacetic acid.
Iodoacetic acid (CAS 64-69-7) References
- Iodoacetic acid, but not sodium iodate, creates an inducible swine model of photoreceptor damage. | Noel, JM., et al. 2012. Exp Eye Res. 97: 137-47. PMID: 22251455
- The effects of iodoacetic acid on the mouse retina. | Rösch, S., et al. 2015. Graefes Arch Clin Exp Ophthalmol. 253: 25-35. PMID: 24827634
- Iodoacetic acid activates Nrf2-mediated antioxidant response in vitro and in vivo. | Wang, S., et al. 2014. Environ Sci Technol. 48: 13478-88. PMID: 25332096
- Iodoacetic acid inhibits follicle growth and alters expression of genes that regulate apoptosis, the cell cycle, estrogen receptors, and ovarian steroidogenesis in mouse ovarian follicles. | Gonsioroski, A., et al. 2020. Reprod Toxicol. 91: 101-108. PMID: 31693920
- The porcine iodoacetic acid model of retinal degeneration: Morpho-functional characterization of the visual system. | Barone, F., et al. 2020. Exp Eye Res. 193: 107979. PMID: 32087230
- Iodoacetic acid disrupts mouse oocyte maturation by inducing oxidative stress and spindle abnormalities. | Jiao, X., et al. 2021. Environ Pollut. 268: 115601. PMID: 33126034
- Iodoacetic acid affects estrous cyclicity, ovarian gene expression, and hormone levels in mice†. | Gonsioroski, A., et al. 2021. Biol Reprod. 105: 1030-1042. PMID: 34086879
- Iodoacetic Acid, a Water Disinfection Byproduct, Disrupts Hypothalamic, and Pituitary Reproductive Regulatory Factors and Induces Toxicity in the Female Pituitary. | Gonzalez, RVL., et al. 2021. Toxicol Sci. 184: 46-56. PMID: 34453833
- Metabolic Analysis of Schizochytrium Mutants With High DHA Content Achieved With ARTP Mutagenesis Combined With Iodoacetic Acid and Dehydroepiandrosterone Screening. | Zeng, L., et al. 2021. Front Bioeng Biotechnol. 9: 738052. PMID: 34869256
- Effects of prenatal and lactational exposure to iodoacetic acid on the F1 generation of mice†. | Gonsioroski, A., et al. 2022. Biol Reprod. 107: 650-663. PMID: 35470848
- Iodoacetic acid exposure alters the transcriptome in mouse ovarian antral follicles. | Gonsioroski, A., et al. 2022. J Environ Sci (China). 117: 46-57. PMID: 35725088
- Effects of iodoacetic acid drinking water disinfection byproduct on the gut microbiota and its metabolism in rats. | Sha, Y., et al. 2022. J Environ Sci (China). 117: 91-104. PMID: 35725093
- Effect of iodoacetic acid on the reproductive system of male mice. | Liang, Y., et al. 2022. Front Pharmacol. 13: 958204. PMID: 36091762
- Drinking water disinfection byproduct iodoacetic acid affects thyroid hormone synthesis in Nthy-ori 3-1 cells. | Xiao, J., et al. 2023. Ecotoxicol Environ Saf. 257: 114926. PMID: 37094483
Inhibitor of:
4930443G12Rik, Acetyl-CoA Synthetase, Aldolase B, ATP8, DMGDH, FAM173B, G3PP, GLYCTK, Morc2b, MTRF1, NDUFB7, Olfr1044, Olfr560, Olfr57, OR10A7, PGM 1, Protamine 2, PTRH2, SCOCO, SFXN5, Shank 2, SLC25A35, SLC25A48, TMPPE, Tomm5, USMG5, and Vmn2r106.Activator of:
AK2, Amylase 2a5, ATP5D, band 3, Olfr888, Olfr889, Olfr890, p-Tyr, and Slc16a5.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Iodoacetic acid, 10 g | sc-215183 | 10 g | $56.00 | |||
Iodoacetic acid, 25 g | sc-215183A | 25 g | $97.00 |