Iodixanol (CAS 92339-11-2)

Iodixanol is a non-ionic, iso-osmolar contrast agent primarily utilized in the field of research for diagnostic imaging, including X-ray and computed tomography (CT) scans, to enhance the visualization of body structures such as blood vessels, organs, and tissues. Its mechanism of action involves the high atomic number of iodine, which allows iodixanol to absorb X-rays more effectively than surrounding tissues, thereby creating a contrast that delineates anatomical features with greater clarity. This characteristic makes it invaluable for studies aimed at understanding the intricate details of vascular diseases, the architecture of organ systems, and the progression of pathologies in model organisms. Iodixanol′s iso-osmolar property, where its osmolality is similar to that of blood, minimizes the risk of osmotic shock in experimental applications, making it a preferred choice for applications requiring high fidelity and minimal physiological disturbance to the subjects under examination. Its role in research extends beyond mere imaging enhancement to include applications in cell biology, where it is used in density gradient centrifugation for the separation and purification of cells, viruses, and subcellular organelles, thereby contributing to a broader understanding of cellular functions and disease mechanisms.