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Integrin β7 Antibody (LS722) is a rat monoclonal IgG antibody that detects Integrin β7 in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), and flow cytometry (FCM). Integrin β7 is a crucial component of the integrin family, functioning primarily as a receptor that mediates cell adhesion and communication with the extracellular matrix. Integrin β7 is predominantly expressed on the surface of immune cells, particularly in the gut-associated lymphoid tissue, where Integrin β7 plays a vital role in the homing of lymphocytes to the intestinal mucosa. The ability of Integrin β7 to interact with its ligands, such as mucosal addressin cell adhesion molecule-1 (MAdCAM-1), is essential for the recruitment of immune cells to sites of inflammation and for maintaining gut immune homeostasis. Furthermore, proper functioning of Integrin β7 is critical for the regulation of immune responses, and dysregulation of Integrin β7 has been implicated in various inflammatory diseases, including inflammatory bowel disease. Anti-Integrin β7 antibody (LS722) provides a valuable tool for researchers studying the dynamics of immune cell trafficking and the underlying mechanisms of immune-related disorders.
Ordering Information
Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Integrin β7/ITGB7 Antibody (LS722) | sc-53545 | 200 µg/ml | $316.00 | |||
Integrin β7/ITGB7 Antibody (LS722) FITC | sc-53545 FITC | 200 µg/ml | $330.00 | |||
Integrin β7/ITGB7 Antibody (LS722) L | sc-53545 L | 200 µg/0.1 ml | $316.00 | |||
Integrin β7/ITGB7 Antibody (LS722) PE | sc-53545 PE | 200 µg/ml | $343.00 |