Integrin β3/ITGB3/CD61 Antibody (NaM28-7D6): sc-51738

Integrin β3 Antibody (NaM28-7D6) is a mouse monoclonal IgG1 antibody that detects Integrin β3 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and flow cytometry (FCM). Integrin β3 is a crucial component of the integrin family, functioning as a receptor that mediates cell adhesion to the extracellular matrix and plays a significant role in various cellular processes. Anti-Integrin β3 antibody (NaM28-7D6) recognizes a protein primarily located on the cell surface, where Integrin β3 forms heterodimers with Integrin α subunits, such as αv, to create functional receptors that interact with ligands like fibronectin and vitronectin. Integrin β3 localization at the cell membrane is vital for facilitating cell signaling and communication, which are essential for processes such as wound healing, immune response, and tissue repair. Furthermore, Integrin β3 interaction with ligands not only promotes cell adhesion but also triggers intracellular signaling pathways that influence cell behavior, including migration and proliferation. Integrin β3 monoclonal antibody (NaM28-7D6) enables researchers to gain insights into the dynamics of cell adhesion and the underlying mechanisms of various diseases, including cancer and cardiovascular disorders, where integrin signaling is often dysregulated.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

The preferred Integrin αV/β3/CD51/CD61 antibody is Integrin αV/β3/CD51/CD61 Antibody (23C6): sc-7312.