Integrin β1/ITGB1 Antibody (MEM-101A): sc-51649

Integrin β1 Antibody (MEM-101A) is a mouse monoclonal IgG1 antibody that detects Integrin β1 in human samples through western blotting (WB) under non-reducing conditions, immunoprecipitation (IP), and flow cytometry (FCM). Integrin β1 is a crucial component of the integrin family, consisting of heterodimers formed by noncovalently associated transmembrane α and β subunits. Anti-Integrin β1 antibody (MEM-101A) recognizes a protein that plays a vital role in mediating cell adhesion to the extracellular matrix and is involved in various cellular processes, including signaling pathways that regulate cell growth, differentiation, migration, and apoptosis. Integrin β1 forms more than 20 different receptor combinations when paired with various α subunits, enabling diverse interactions with ligands such as fibronectin, collagen, and vitronectin. These interactions maintain tissue integrity and facilitate communication between cells and their environment. Integrin β1 binding to soluble ligands and counterreceptors on adjacent cells, such as intracellular adhesion molecules (ICAMs), underscores Integrin β1′s significance in promoting cell aggregation and modulating immune responses. Anti-Integrin β1 antibody (MEM-101A) serves as an invaluable tool for researchers studying integrin roles in cellular dynamics and disease implications.

The preferred Integrin β1/ITGB1 antibody is Integrin β1/ITGB1 Antibody (K-20): sc-18887.