Date published: 2026-5-18

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Integrin α3a/ITGA3A Antibody (29A3): sc-59966

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Datasheets
  • Integrin α3a/ITGA3A Antibody (29A3) is a mouse monoclonal IgG1 Integrin α3a/ITGA3A antibody provided at 100 µg/ml
  • raised against Integrin αIIIa of human origin
  • recommended for detection of Integrin αIIIa of mouse, rat and human origin by WB and IF
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for Integrin α3a/ITGA3A Antibody (29A3). This work is in progress.
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    Integrin αIIIa Antibody (29A3) is a mouse monoclonal IgG1 antibody that detects Integrin alpha IIIa protein of mouse, rat, and human origin by western blotting (WB) and immunofluorescence (IF). Anti-Integrin alpha IIIa antibody (29A3) is available as the non-conjugated form. Integrin alpha IIIa protein, also known as CD49c, plays a crucial role in cell adhesion and signaling, functioning as a receptor that mediates interactions between cells and the extracellular matrix. Integrin alpha IIIa (29A3) antibody recognizes a protein primarily located on the cell surface, where Integrin alpha IIIa forms heterodimers with β subunits to create integrin receptors that bind to various ligands, including fibronectin and collagen. Integrin alpha IIIa′s ability to interact with these extracellular matrix components is vital for processes such as cell migration, tissue repair, and immune responses. Anti-Integrin alpha IIIa antibody (29A3) helps researchers study signaling pathways essential for regulating cellular functions like growth and differentiation, making Integrin alpha IIIa a key player in maintaining tissue homeostasis and responding to injury. Integrin alpha IIIa (29A3) monoclonal antibody serves as an invaluable tool for researchers studying these critical biological processes and the underlying mechanisms of diseases related to cell adhesion and migration.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    Integrin α3a/ITGA3A Antibody (29A3) References:

    1. Ligand binding promotes the entropy-driven oligomerization of integrin alpha IIb beta 3.  |  Hantgan, RR., et al. 2003. J Biol Chem. 278: 3417-26. PMID: 12426312
    2. Integrin alpha IIb beta 3-dependent calcium signals regulate platelet-fibrinogen interactions under flow. Involvement of phospholipase C gamma 2.  |  Goncalves, I., et al. 2003. J Biol Chem. 278: 34812-22. PMID: 12832405
    3. SHIP1 and Lyn Kinase Negatively Regulate Integrin alpha IIb beta 3 signaling in platelets.  |  Maxwell, MJ., et al. 2004. J Biol Chem. 279: 32196-204. PMID: 15166241
    4. Disabled-2 is a negative regulator of integrin alpha(IIb)beta(3)-mediated fibrinogen adhesion and cell signaling.  |  Huang, CL., et al. 2004. J Biol Chem. 279: 42279-89. PMID: 15280374
    5. Integrins: versatility, modulation, and signaling in cell adhesion.  |  Hynes, RO. 1992. Cell. 69: 11-25. PMID: 1555235
    6. Integrins and signal transduction pathways: the road taken.  |  Clark, EA. and Brugge, JS. 1995. Science. 268: 233-9. PMID: 7716514
    7. Synergistic roles for receptor occupancy and aggregation in integrin transmembrane function.  |  Miyamoto, S., et al. 1995. Science. 267: 883-5. PMID: 7846531
    8. Epithelial integrins.  |  Sheppard, D. 1996. Bioessays. 18: 655-60. PMID: 8760339
    9. Cooperation between soluble factors and integrin-mediated cell anchorage in the control of cell growth and differentiation.  |  Juliano, R. 1996. Bioessays. 18: 911-7. PMID: 8939069

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    Integrin α3a/ITGA3A Antibody (29A3)

    sc-59966
    100 µg/ml
    $322.00