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Inosine 5′-triphosphate trisodium salt (CAS 35908-31-7)

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Alternate Names:
ITP
Application:
Inosine 5′-triphosphate trisodium salt is a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase
CAS Number:
35908-31-7
Purity:
≥95%
Molecular Weight:
574.11
Molecular Formula:
C10H12Na3N4O14P3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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InInosine 5′-triphosphate trisodium salt is used in studies on the impact of deamination of ATP and GTP by various enzymes and chemical processes. Inosine 5′-triphosphate trisodium salt may be used as a substrate to study the specificity and kinetics of nucleoside-5′-triphosphatase and ATPase. ITP is also used to study activation of various ATPases and GTPases. Inosine-5′-triphosphate trisodium salt (ITP) is a naturally occurring nucleotide salt present in all living organisms. It has been extensively utilized in scientific research for various purposes. Serving as a precursor to adenosine triphosphate (ATP), the vital energy molecule for cellular functions, Inosine 5′-triphosphate trisodium salt holds significant importance. Its applications in scientific investigations encompass studying ATP′s involvement in essential cellular processes like cell respiration, metabolism, and energy transfer. Numerous in vivo studies have demonstrated the efficacy of Inosine-5′-triphosphate trisodium salt as useful for investigating ATP′s role.


Inosine 5′-triphosphate trisodium salt (CAS 35908-31-7) References

  1. Ecto-nucleotidases and nucleoside transporters mediate activation of adenosine receptors on hippocampal mossy fibers by P2X7 receptor agonist 2'-3'-O-(4-benzoylbenzoyl)-ATP.  |  Kukley, M., et al. 2004. J Neurosci. 24: 7128-39. PMID: 15306646
  2. Trigger loop folding determines transcription rate of Escherichia coli's RNA polymerase.  |  Mejia, YX., et al. 2015. Proc Natl Acad Sci U S A. 112: 743-8. PMID: 25552559
  3. Nucleotides, micro- and macro-nutrients, limonoids, flavonoids, and hydroxycinnamates composition in the phloem sap of sweet orange.  |  Hijaz, F., et al. 2016. Plant Signal Behav. 11: e1183084. PMID: 27171979
  4. Atropine resistant excitation of the urinary bladder: the possibility of transmission via nerves releasing a purine nucleotide.  |  Burnstock, G., et al. 1972. Br J Pharmacol. 44: 451-61. PMID: 4339250
  5. Fine structural localization of adenosine triphosphatase activities in the saccus vasculosus of the rainbow trout, Salmo gairdneri Richardson.  |  Jansen, WF., et al. 1981. Cell Tissue Res. 219: 267-79. PMID: 6456069
  6. UTP induces vascular responses in the isolated and perfused canine epicardial coronary artery via UTP-preferring P2Y receptors.  |  Matsumoto, T., et al. 1997. Br J Pharmacol. 122: 1625-32. PMID: 9422807

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Inosine 5′-triphosphate trisodium salt, 50 mg

sc-215180
50 mg
$40.00

Inosine 5′-triphosphate trisodium salt, 100 mg

sc-215180A
100 mg
$65.00