Ingenol 3,20-dibenzoate (CAS 59086-90-7)
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Ingenol 3,20-dibenzoate is used in biochemical research to investigate signal transduction pathways, especially those involving protein kinase C (PKC), as it acts as an agonist to this family of enzymes. Researchers utilize ingenol 3,20-dibenzoate to explore the structure-activity relationships that govern the interactions between PKC isoforms and their ligands. Moreover, the compound is employed in studies focusing on cell growth and death, providing insights into the regulation of these fundamental processes at the molecular level. Its role in inducing biological responses by activating PKC has also made ingenol 3,20-dibenzoate useful in the elucidation of cellular mechanisms that are controlled by this kinase, such as the release of neurotransmitters and the modulation of other cellular responses.
Ingenol 3,20-dibenzoate (CAS 59086-90-7) References
- Biphasic Effects of Ingenol 3,20-Dibenzoate on the Erythropoietin Receptor: Synergism at Low Doses and Antagonism at High Doses. | Oh, JG., et al. 2015. Mol Pharmacol. 88: 392-400. PMID: 26048958
- Enhancement of NK cell-mediated lysis of non-small lung cancer cells by nPKC activator, ingenol 3,20 dibenzoate. | Gong, C., et al. 2017. Mol Immunol. 83: 23-32. PMID: 28092804
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ingenol 3,20-dibenzoate, 1 mg | sc-202663 | 1 mg | $600.00 | |||
Ingenol 3,20-dibenzoate, 5 mg | sc-202663A | 5 mg | $2400.00 | |||
Ingenol 3,20-dibenzoate, 10 mg | sc-202663B | 10 mg | $3500.00 | |||
Ingenol 3,20-dibenzoate, 100 mg | sc-202663C | 100 mg | $24000.00 |