Influenza B Antibody (1C2): sc-101353

Influenza B Antibody (1C2) is a mouse monoclonal IgG1 antibody that detects Influenza B protein through western blotting (WB), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Influenza B antibody (1C2) is available as a non-conjugated format. Influenza B virus, part of the Orthomyxoviridae family, undergoes frequent antigenic changes to evade host immune response. Nucleoprotein (NP) associated with Influenza B plays a vital role in viral life cycle by encapsidating viral RNA genome and forming ribonucleoprotein complexes essential for viral replication and transcription. NP protein maintains viral genome stability and aids in transporting viral RNA from nucleus to cytoplasm for protein translation necessary in new virion assembly. Understanding NP protein function proves crucial for antiviral strategy development and vaccine design, serving as a target for host immune response. Influenza A causes pandemics, while Influenza B typically leads to milder seasonal flu illnesses, emphasizing the need to monitor and study these viral proteins for public health management.

Alexa Fluor^® is a trademark of Molecular Probes Inc., OR., USA

LI-COR^® and Odyssey^® are registered trademarks of LI-COR Biosciences

Influenza B Antibody (1C2) References:

1. Coinfection with influenza B virus does not affect association of Neisseria meningitidis with human nasopharyngeal mucosa in organ culture.  |  Read, RC., et al. 1999. Infect Immun. 67: 3082-6. PMID: 10338524
2. Influenza B virus in seals.  |  Osterhaus, AD., et al. 2000. Science. 288: 1051-3. PMID: 10807575
3. Influenza B and C virus NEP (NS2) proteins possess nuclear export activities.  |  Paragas, J., et al. 2001. J Virol. 75: 7375-83. PMID: 11462009
4. Influenza A and B virus infections in children.  |  Peltola, V., et al. 2003. Clin Infect Dis. 36: 299-305. PMID: 12539071
5. Epidemics of two Victoria and Yamagata influenza B lineages in Yamagata, Japan.  |  Mizuta, K., et al. 2004. Epidemiol Infect. 132: 721-6. PMID: 15310174
6. Detection and characterization of new influenza B virus variants in 2002.  |  Chi, XS., et al. 2005. J Clin Microbiol. 43: 2345-9. PMID: 15872264
7. Sequential mutations in hemagglutinins of influenza B virus isolates: definition of antigenic domains.  |  Krystal, M., et al. 1983. Proc Natl Acad Sci U S A. 80: 4527-31. PMID: 6192436
8. Serological diagnosis of influenza B virus infection: comparison of an enzyme-linked immunosorbent assay and the hemagglutination inhibition test.  |  Turner, R., et al. 1982. J Clin Microbiol. 15: 824-9. PMID: 7047553

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Influenza B Antibody (1C2) has 0 citations in a variety of scientific publications.

Primary antibodies for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Influenza B Antibody (1C2) Specifications

Alternate Product Name: Influenza B

Product Clone Name: 1C2

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁

Amino Acids:

Epitope Target: Influenza B Virus NP

Epitope Species:

Product Reactivity/Detection: an Influenza B virus group specific antigen

Species Reactivity/Detection: NSR

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IF, ELISA

Vialing Information: Each vial contains 50 µg IgG₁ in 0.5 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 0 citations in various scientific publications

Available Conjugates/Forms for Influenza B Antibody (1C2): N/A