Date published: 2026-4-30

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Indoprofen (CAS 31842-01-0)

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Alternate Names:
α-Methyl-p-(1-oxo-2-isoindolinyl)benzeneacetic acid
CAS Number:
31842-01-0
Molecular Weight:
281.31
Molecular Formula:
C17H15NO3
Supplemental Information:
This is as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Indoprofen is classified as an Indoprofen, meaning it operates by inhibiting specific enzymes known as cyclooxygenases (COX). These enzymes play a role in generating prostaglandins, which are hormones responsible for inflammation and pain. By obstructing the function of COX enzymes, indoprofen diminishes the production of prostaglandins. This reduces inflammation and pain, making it an effective treatment for conditions such as arthritis and headaches.


Indoprofen (CAS 31842-01-0) References

  1. A three-component coupling process based on vicarious nucleophilic substitution (VNS(AR))-alkylation reactions: an approach to indoprofen and derivatives.  |  Lawrence, NJ., et al. 2002. J Org Chem. 67: 457-64. PMID: 11798318
  2. Photochemical and photophysical properties of indoprofen.  |  Lhiaubet-Vallet, V., et al. 2003. Photochem Photobiol. 77: 487-91. PMID: 12812289
  3. Indoprofen upregulates the survival motor neuron protein through a cyclooxygenase-independent mechanism.  |  Lunn, MR., et al. 2004. Chem Biol. 11: 1489-93. PMID: 15555999
  4. Indoprofen prevents muscle wasting in aged mice through activation of PDK1/AKT pathway.  |  Kim, H., et al. 2020. J Cachexia Sarcopenia Muscle. 11: 1070-1088. PMID: 32096917
  5. Indoprofen exerts a potent therapeutic effect against sepsis by alleviating high mobility group box 1-mediated inflammatory responses.  |  Bi, X., et al. 2021. Toxicol Appl Pharmacol. 433: 115778. PMID: 34755645
  6. Indoprofen, a non-steroidal anti-inflammatory analgesic which does not depress respiration in normal man. A study comparing indoprofen with morphine.  |  Love, AJ., et al. 1985. S Afr Med J. 68: 801-2. PMID: 3934769
  7. Indoprofen in juvenile chronic arthritis.  |  Price, T., et al. 1985. Clin Exp Rheumatol. 3: 59-62. PMID: 3978896
  8. Some novel observations of a drug (indoprofen)--albumin interaction.  |  Juni, K., et al. 1983. Biopharm Drug Dispos. 4: 1-7. PMID: 6838999
  9. Kinetic interaction of glipizide and indoprofen in healthy volunteers.  |  Melander, A. and Wåhlin-Boll, E. 1980. Acta Endocrinol Suppl (Copenh). 239: 9-10. PMID: 6933822
  10. Pharmacokinetics and metabolism of indoprofen in the hamster.  |  Goldaniga, GC., et al. 1980. Arzneimittelforschung. 30: 1654-8. PMID: 7192105
  11. High-pressure liquid chromatographic determination of acetylsalicylic acid, salicylic acid, diflunisal, indomethacin, indoprofen and indobufen.  |  Wåhlin-Boll, E., et al. 1981. Eur J Clin Pharmacol. 20: 375-8. PMID: 7286048
  12. Human pharmacokinetics of indoprofen.  |  Tamassia, V. 1981. Eur J Rheumatol Inflamm. 4: 11-5. PMID: 7341274
  13. Evaluation of the long-term efficacy and safety of indoprofen in rheumatoid arthritis and osteoarthritis patients.  |  Cagianelli, MA., et al. 1981. Eur J Rheumatol Inflamm. 4: 144-50. PMID: 7341275
  14. Interaction of glipizide and indoprofen.  |  Melander, A. and Wåhlin-Boll, E. 1981. Eur J Rheumatol Inflamm. 4: 22-5. PMID: 7341277

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Indoprofen, 10 mg

sc-211643
10 mg
$276.00