Molecular structure of Indomethacin Methyl Ester, CAS Number: 1601-18-9
Indomethacin Methyl Ester (CAS 1601-18-9)
Application:
Indomethacin Methyl Ester is a selective COX-2 inhibitor
CAS Number:
1601-18-9
Molecular Weight:
371.81
Molecular Formula:
C20H18ClNO4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Selective COX-2 inhibitor
Indomethacin Methyl Ester (CAS 1601-18-9) References
- Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. | Kalgutkar, AS., et al. 2000. J Med Chem. 43: 2860-70. PMID: 10956194
- Structural determinants of arylacetic acid nonsteroidal anti-inflammatory drugs necessary for binding and activation of the prostaglandin D2 receptor CRTH2. | Hata, AN., et al. 2005. Mol Pharmacol. 67: 640-7. PMID: 15563582
- Topography of prostaglandin H synthase. Antiinflammatory agents and the protease-sensitive arginine 253 region. | Kulmacz, RJ. 1989. J Biol Chem. 264: 14136-44. PMID: 2503512
- Binding of indomethacin methyl ester to cyclooxygenase-2. A computational study. | Sárosi, MB. 2018. J Mol Model. 24: 150. PMID: 29869728
- Reductive Electrophotocatalysis: Merging Electricity and Light To Achieve Extreme Reduction Potentials. | Kim, H., et al. 2020. J Am Chem Soc. 142: 2087-2092. PMID: 31951390
- Comparison of Drug Release and Adsorption under Supersaturating Conditions for Ordered Mesoporous Silica with Indomethacin or Indomethacin Methyl Ester. | McCarthy, CA., et al. 2020. Mol Pharm. 17: 3062-3074. PMID: 32633973
- Structure determination, thermal stability and dissolution rate of δ-indomethacin. | Andrusenko, I., et al. 2021. Int J Pharm. 608: 121067. PMID: 34481012
- Development of substituted benzylidene derivatives as novel dual cholinesterase inhibitors for Alzheimer's treatment. | Gupta, SM., et al. 2023. RSC Adv. 13: 26344-26356. PMID: 37671344
- Does Media Choice Matter When Evaluating the Performance of Hydroxypropyl Methylcellulose Acetate Succinate-Based Amorphous Solid Dispersions? | Bapat, P., et al. 2023. Mol Pharm. 20: 5714-5727. PMID: 37751517
Inhibitor of:
Cox-2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Indomethacin Methyl Ester, 10 mg | sc-207757 | 10 mg | $300.00 |