Molecular structure of Indomethacin Ester, 4-Methoxyphenyl-, CAS Number: 261766-24-9
Indomethacin Ester, 4-Methoxyphenyl- (CAS 261766-24-9)
Alternate Names:
1-(p-Chlorobenzoyl)-5-methoxy-2-methyl-1H-indole-3-acetic Acid, 4-Methoxyphenyl Ester
Application:
Indomethacin Ester, 4-Methoxyphenyl- is a potent and selective inhibitor of COX-2
CAS Number:
261766-24-9
Molecular Weight:
463.91
Molecular Formula:
C26H22ClNO5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Indomethacin Ester, 4-Methoxyphenyl- is a cell-permeable 4-methoxyphenyl ester derivative of the non-steroidal anti-inflammatory drug (NSAID) Indomethacin . A potent and selective inhibitor of COX-2 compared to COX-1.
Indomethacin Ester, 4-Methoxyphenyl- (CAS 261766-24-9) References
- Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors. | Kalgutkar, AS., et al. 2000. Proc Natl Acad Sci U S A. 97: 925-30. PMID: 10639181
- Ester and amide derivatives of the nonsteroidal antiinflammatory drug, indomethacin, as selective cyclooxygenase-2 inhibitors. | Kalgutkar, AS., et al. 2000. J Med Chem. 43: 2860-70. PMID: 10956194
- Inhibition of fatty acid amide hydrolase, a key endocannabinoid metabolizing enzyme, by analogues of ibuprofen and indomethacin. | Holt, S., et al. 2007. Eur J Pharmacol. 565: 26-36. PMID: 17397826
Inhibitor of:
Cox-2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Indomethacin Ester, 4-Methoxyphenyl-, 5 mg | sc-221757 | 5 mg | $340.00 |