Indolmycin (CAS 21200-24-8)
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Indolmycin is a natural product that functions as an inhibitor of bacterial protein synthesis. It specifically targets the bacterial enzyme tryptophanyl-tRNA synthetase, which is essential for the incorporation of tryptophan into proteins during translation. By binding to the active site of this enzyme, indolmycin disrupts the formation of aminoacyl-tRNA complexes, ultimately inhibiting protein synthesis in bacteria. This mechanism of action is for the bacteriostatic effect of indolmycin, as it prevents the production of essential proteins necessary for bacterial growth and survival. Additionally, indolmycin exhibits selectivity for bacterial tryptophanyl-tRNA synthetase over the human homolog, making it a promising candidate for the development of novel antibacterial agents. Overall, indolmycin′s ability to interfere with bacterial protein synthesis through its interaction with tryptophanyl-tRNA synthetase highlights its potential as useful for studying bacterial translation.
Indolmycin (CAS 21200-24-8) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Indolmycin, 1 mg | sc-202183 | 1 mg | $373.00 |