Indole-3-lactic Acid (CAS 1821-52-9)
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Alternate Names:
2-Hydroxy-3-(3-indolyl)propionic Acid
CAS Number:
1821-52-9
Molecular Weight:
205.21
Molecular Formula:
C11H11NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Indole-3-lactic acid functions as a signaling molecule within cells, playing a role in various cellular processes. It interacts with cellular receptors and enzymes, modulating gene expression and influencing the activity of specific proteins. The mechanism of action involves the binding of indole-3-lactic acid to its target molecules, leading to the activation or inhibition of downstream signaling pathways. This ultimately affects cellular processes such as growth, differentiation, and metabolism. Its interactions with cellular or molecular components contribute to the homeostasis and function of the cell.
Indole-3-lactic Acid (CAS 1821-52-9) References
- Indole-3-acetic acid biosynthetic pathways in the basidiomycetous yeast Rhodosporidium paludigenum. | Nutaratat, P., et al. 2016. Arch Microbiol. 198: 429-37. PMID: 26899734
- Production of Indole-3-Lactic Acid by Bifidobacterium Strains Isolated fromHuman Infants. | Sakurai, T., et al. 2019. Microorganisms. 7: PMID: 31514325
- Biosynthetic pathway of indole-3-acetic acid in ectomycorrhizal fungi collected from northern Thailand. | Kumla, J., et al. 2020. PLoS One. 15: e0227478. PMID: 31899917
- Indole-3-lactic acid, a metabolite of tryptophan, secreted by Bifidobacterium longum subspecies infantis is anti-inflammatory in the immature intestine. | Meng, D., et al. 2020. Pediatr Res. 88: 209-217. PMID: 31945773
- Neonatal diet alters fecal microbiota and metabolome profiles at different ages in infants fed breast milk or formula. | Brink, LR., et al. 2020. Am J Clin Nutr. 111: 1190-1202. PMID: 32330237
- Indole-3-lactic acid associated with Bifidobacterium-dominated microbiota significantly decreases inflammation in intestinal epithelial cells. | Ehrlich, AM., et al. 2020. BMC Microbiol. 20: 357. PMID: 33225894
- The impact of indole-3-lactic acid on immature intestinal innate immunity and development: a transcriptomic analysis. | Huang, W., et al. 2021. Sci Rep. 11: 8088. PMID: 33850185
- Bifidobacteria-mediated immune system imprinting early in life. | Henrick, BM., et al. 2021. Cell. 184: 3884-3898.e11. PMID: 34143954
- Lactobacillus gallinarum modulates the gut microbiota and produces anti-cancer metabolites to protect against colorectal tumourigenesis. | Sugimura, N., et al. 2021. Gut. 71: 2011-21. PMID: 34937766
- Ginsenoside Rg1 Alleviates Acute Ulcerative Colitis by Modulating Gut Microbiota and Microbial Tryptophan Metabolism. | Cheng, H., et al. 2022. Front Immunol. 13: 817600. PMID: 35655785
- Effects of Indole-3-Lactic Acid, a Metabolite of Tryptophan, on IL-4 and IL-13-Induced Human Skin-Equivalent Atopic Dermatitis Models. | Kim, K., et al. 2022. Int J Mol Sci. 23: PMID: 36362303
- The gut microbiome and hypertension. | O'Donnell, JA., et al. 2023. Nat Rev Nephrol. 19: 153-167. PMID: 36631562
- Indole-3-lactic acid as a tryptophan metabolite produced by Bifidobacterium spp. | Aragozzini, F., et al. 1979. Appl Environ Microbiol. 38: 544-6. PMID: 533277
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Indole-3-lactic Acid, 100 mg | sc-489732 | 100 mg | $148.00 | |||
Indole-3-lactic Acid, 500 mg | sc-489732A | 500 mg | $322.00 | |||
Indole-3-lactic Acid, 1 g | sc-489732B | 1 g | $530.00 |