Indole (CAS 120-72-9)
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Indole is a chemical compound that functions as a signaling molecule in various biological processes. It acts as a precursor for the biosynthesis of tryptophan, an essential amino acid, and is involved in the regulation of gene expression. Indole exerts its mechanism of action by interacting with specific receptors and enzymes, modulating cellular signaling pathways and gene transcription. It plays a role in the regulation of bacterial biofilm formation and virulence, as well as in the communication between microorganisms. Indole has been found to influence the behavior of certain organisms by serving as a chemical cue. At the molecular level, indole interacts with target proteins and receptors, leading to downstream effects on cellular processes. Its presence can impact the behavior and physiology of organisms, making it a relevant molecule in various experimental applications.
Indole (CAS 120-72-9) References
- The indole pulse: a new perspective on indole signalling in Escherichia coli. | Gaimster, H., et al. 2014. PLoS One. 9: e93168. PMID: 24695245
- Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives. | Sherer, C. and Snape, TJ. 2015. Eur J Med Chem. 97: 552-60. PMID: 25466446
- Product in indole detection by Ehrlich's reagent. | Lamb, AC., et al. 2015. Anal Biochem. 484: 21-3. PMID: 25958008
- Multi-Target Directed Indole Based Hybrid Molecules in Cancer Therapy : An Up-To-Date Evidence-Based Review. | Sunil, D. and Kamath, PR. 2017. Curr Top Med Chem. 17: 959-985. PMID: 27697057
- Indole and indoxyl sulfate, gut bacteria metabolites of tryptophan, change arterial blood pressure via peripheral and central mechanisms in rats. | Huć, T., et al. 2018. Pharmacol Res. 130: 172-179. PMID: 29287686
- Catalytic asymmetric synthesis of indole derivatives as novel α-glucosidase inhibitors in vitro. | Islam, MS., et al. 2018. Bioorg Chem. 79: 350-354. PMID: 29807208
- Synthetic strategies, SAR studies, and computer modeling of indole 2 and 3-carboxamides as the strong enzyme inhibitors: a review. | Chehardoli, G. and Bahmani, A. 2021. Mol Divers. 25: 535-550. PMID: 32394235
- The importance of indole and azaindole scaffold in the development of antitumor agents. | Han, Y., et al. 2020. Eur J Med Chem. 203: 112506. PMID: 32688198
- Indole Glycosides from Calanthe discolor with Proliferative Activity on Human Hair Follicle Dermal Papilla Cells. | Morikawa, T., et al. 2021. Chem Pharm Bull (Tokyo). 69: 464-471. PMID: 33952856
- Recent developments in green approaches for sustainable synthesis of indole-derived scaffolds. | Nasri, S., et al. 2022. Mol Divers. 26: 3411-3445. PMID: 35031935
- A Mild Two-Step Synthesis of Structurally Valuable Indole-Fused Derivatives. | Chen, S., et al. 2022. J Org Chem. 87: 3212-3222. PMID: 35152695
- Dip-and-Read, Organic Solvent-Compatible, Paper-Based Analytical Devices Equipped with Chromatographic Separation for Indole Analysis in Shrimp. | Seetasang, S. and Kaneta, T. 2022. ACS Sens. 7: 1194-1200. PMID: 35404587
- Recent progress in biologically active indole hybrids: a mini review. | Mahmoud, E., et al. 2022. Pharmacol Rep. 74: 570-582. PMID: 35594012
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Indole, 25 g | sc-257606 | 25 g | $29.00 | |||
Indole, 100 g | sc-257606A | 100 g | $68.00 | |||
Indole, 250 g | sc-257606B | 250 g | $122.00 | |||
Indole, 1 kg | sc-257606C | 1 kg | $265.00 | |||
Indole, 5 kg | sc-257606D | 5 kg | $1275.00 |