Impentamine dihydrobromide CAS: 34973-91-6
MF: C8H15N3•2HBr
MW: 315.05
A selective H3 receptor antagonist.

Impentamine dihydrobromide (CAS 34973-91-6)

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Application: A selective H3 receptor antagonist
CAS Number: 34973-91-6
Molecular Weight: 315.05
Molecular Formula: C8H15N32HBr
* Refer to Certificate of Analysis for lot specific data (including water content).
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Impentamine dihydrobromide is a selective H3 receptor antagonist. This compound displays >30000-fold selectivity over H1 and H2 receptors. In SK-N-MC cells expressing human H3 receptors, this can act as a partial agonist. Impentamine dihydrobromide also displays antinociceptive properties, possibly via a non-H1 -H2 or -H3 receptor-mediated mechanism.


References

1. Vollinga, R.C., et al. 1995. J. Med. Chem. 38: 266-271.
2. Hough, L.B., et al. 1999. Life Sci. 64: PL79-86.
3. Wieland, K., et al. 2001. J. Pharmacol. Exp. Ther. 299: 908-914.

Solubility :
Soluble to 100 mM in Water and to 100 mM in DMSO
Storage :
Desiccate at room temperature
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Download SDS (MSDS)

Certificate of Analysis

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