Date published: 2025-12-14

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Imipramine (CAS 50-49-7)

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Datasheets
CAS Number:
50-49-7
Molecular Weight:
280.41
Molecular Formula:
C19H24N2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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Imipramine (CAS 50-49-7) References

  1. Imipramine exerts antidepressant-like effects in chronic stress models of depression by promoting CRTC1 expression in the mPFC.  |  Wang, YJ., et al. 2020. Brain Res Bull. 164: 257-268. PMID: 32905805
  2. Imipramine improves visceral sensation and gut barrier in rat models of irritable bowel syndrome.  |  Nozu, T., et al. 2020. Eur J Pharmacol. 887: 173565. PMID: 32946869
  3. Inhibition by Imipramine of the Voltage-Dependent K+ Channel in Rabbit Coronary Arterial Smooth Muscle Cells.  |  An, JR., et al. 2020. Toxicol Sci. 178: 302-310. PMID: 33010168
  4. Effect of imipramine on ether à-go-go potassium channel (Kv1.10) expression in DU145 prostate cancer cells.  |  Söğüt, F., et al. 2022. Andrologia. 54: e14291. PMID: 34729805
  5. Imipramine induces hyperactivity in rats pretreated with ouabain: Implications to the mania switch induced by antidepressants.  |  Valvassori, SS., et al. 2022. J Affect Disord. 299: 425-434. PMID: 34910958
  6. Imipramine activates FAM3A-FOXA2-CPT2 pathway to ameliorate hepatic steatosis.  |  Liu, X., et al. 2022. Metabolism. 136: 155292. PMID: 35995281
  7. Cancer cell autophagy, reprogrammed macrophages, and remodeled vasculature in glioblastoma triggers tumor immunity.  |  Chryplewicz, A., et al. 2022. Cancer Cell. 40: 1111-1127.e9. PMID: 36113478
  8. Acid Sphingomyelinase Inhibitor, Imipramine, Reduces Hippocampal Neuronal Death after Traumatic Brain Injury.  |  Lee, SH., et al. 2022. Int J Mol Sci. 23: PMID: 36499076
  9. Imipramine Induces Apoptosis and Inhibits the Metastatic Potential of Triple-negative Breast Cancer Cells.  |  Chen, SK., et al. 2023. Anticancer Res. 43: 2985-2994. PMID: 37351989
  10. Imipramine Treatment Alters Sphingomyelin, Cholesterol, and Glycerophospholipid Metabolism in Isolated Macrophage Lysosomes.  |  Albright, JM., et al. 2023. Biomolecules. 13: PMID: 38136603

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Imipramine, 5 mg

sc-507545
5 mg
$190.00