![Imidazo[1,2-a]pyrimidine (CAS 274-95-3) - chemical structure image](https://media.scbt.com/product/imidazo1-2-apyrimidine-274-95-3-structure_21_78_b_217826.jpg)
![Imidazo[1,2-a]pyrimidine (CAS 274-95-3) - chemical structure image](https://media.scbt.com/product/imidazo1-2-apyrimidine-274-95-3-structure_21_78_t_217826.jpg "Molecular structure of Imidazo[1,2-a]pyrimidine, CAS Number: 274-95-3")
Molecular structure of Imidazo[1,2-a]pyrimidine, CAS Number: 274-95-3
Imidazo[1,2-a]pyrimidine (CAS 274-95-3)
CAS Number:
274-95-3
Molecular Weight:
119.13
Molecular Formula:
C6H5N3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
Imidazo[1,2-a]pyrimidine is a member of the pyrimidine family and a heterocyclic aromatic compound with diverse applications. Depending on its specific use, Imidazo[1,2-a]pyrimidine exhibits a wide range of mechanisms of action. In the agrochemical sector, it has demonstrated interactions with key enzymes such as acetylcholinesterase, lipoxygenases, and glutathione-S-transferases. In the dye industry, Imidazo[1,2-a]pyrimidine has been found to interact with various proteins, including cytochrome P450 and peroxidases, making it a valuable component in dye formulations.
Imidazo[1,2-a]pyrimidine (CAS 274-95-3) References
- Effect of imidazo[1,2-a]pyrimidine derivatives on leukocyte function. | Vidal, A., et al. 2001. Inflamm Res. 50: 317-20. PMID: 11475333
- Palladium-catalyzed regioselective arylation of imidazo[1,2-a]pyrimidine. | Li, W., et al. 2003. Org Lett. 5: 4835-7. PMID: 14653686
- 8-Fluoroimidazo[1,2-a]pyridine: synthesis, physicochemical properties and evaluation as a bioisosteric replacement for imidazo[1,2-a]pyrimidine in an allosteric modulator ligand of the GABA A receptor. | Humphries, AC., et al. 2006. Bioorg Med Chem Lett. 16: 1518-22. PMID: 16386901
- Generation and exploration of new classes of antitubercular agents: The optimization of oxazolines, oxazoles, thiazolines, thiazoles to imidazo[1,2-a]pyridines and isomeric 5,6-fused scaffolds. | Moraski, GC., et al. 2012. Bioorg Med Chem. 20: 2214-20. PMID: 22391032
- Synthesis and antiproliferative activity of imidazo[1,2-a]pyrimidine Mannich bases. | Aeluri, R., et al. 2015. Eur J Med Chem. 100: 18-23. PMID: 26067381
- Utility of 3-Acetyl-6-bromo-2H-chromen-2-one for the Synthesis of New Heterocycles as Potential Antiproliferative Agents. | Gomha, SM., et al. 2015. Molecules. 20: 21826-39. PMID: 26690106
- A convenient approach for the preparation of imidazo[1,2-a]-fused bicyclic frameworks via IBX/NIS promoted oxidative annulation. | Makra, Z., et al. 2019. Org Biomol Chem. 17: 9001-9007. PMID: 31577318
- Phosphoramidates as Steering Elements for Highly Selective Access to Complementary Imidazo[1,2-a]pyrimidine Isomers. | White, NA., et al. 2019. Org Lett. 21: 9527-9531. PMID: 31738563
- Sequential Regioselective Diorganochalcogenations of Imidazo[1,2-a]pyrimidines Using I2/H3PO4 in Dimethylsulfoxide. | Obah Kosso, AR., et al. 2020. J Org Chem. 85: 3071-3081. PMID: 31984749
- Fluorescent Imidazo[1,2-a]pyrimidine Compounds as Biocompatible Organic Photosensitizers that Generate Singlet Oxygen: A Potential Tool for Phototheranostics. | Lima, MLSO., et al. 2021. Chemistry. 27: 6213-6222. PMID: 33285026
- Microwave assisted, sequential two-step, one-pot synthesis of novel imidazo[1,2-a]pyrimidine containing tri/tetrasubstituted imidazole derivatives. | GÜngÖr, T. 2021. Turk J Chem. 45: 219-230. PMID: 33679165
- Mechanochemical Ruthenium-Catalyzed Ortho-Alkenylation of N-Heteroaryl Arenes with Alkynes under Ball-Milling Conditions. | Bhawani, ., et al. 2022. J Org Chem. 87: 5994-6005. PMID: 35472259
- Synthesis, Optimization, and Structure-Activity Relationships of Imidazo[1,2-a]pyrimidines as Inhibitors of Group 2 Influenza A Viruses. | Alqarni, S., et al. 2022. J Med Chem. 65: 14104-14120. PMID: 36260129
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Imidazo[1,2-a]pyrimidine, 1 g | sc-300827 | 1 g | $129.00 | |||
Imidazo[1,2-a]pyrimidine, 5 g | sc-300827A | 5 g | $520.00 |