Imazalil CAS: 35554-44-0
MF: C14H14Cl2N2O
MW: 297.18
An antifungal agent that may have carcinogenic potential.

Imazalil (CAS 35554-44-0)

  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getAggregateRating, 114ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
Application: Imazalil is an antifungal agent that may have carcinogenic potential
CAS Number: 35554-44-0
Purity: ≥95%
Molecular Weight: 297.18
Molecular Formula: C14H14Cl2N2O
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Imazalil exhibits antifungal activity through inhibition of sterol 14-α demethylase, preventing ergosterol biosynthesis and cell wall formation. Imazalil also inhibits androgen receptors and aromatase through a mixed competitive/noncompetitive mode in vitro. Imazalil exhibits teratogenic effects on vertebrate development, affecting genes involved in retinoic acid signaling and altering neural differentiation in the nervous system.


References

1. Sanderson, J. T., Et al. 2002. Toxicol. Appl. Pharmacol. 182(1): 44-54. PMID: 12127262

2. Smilanick, J. 2008. Postharvest Biology and Technology. 47(2), 226-238

3. Zega, G., Et al. 2009. Aquat. Toxicol. 91(3): 255-261. PMID: 19124165

4. un, X., Et al. 2011. Appl. Microbiol. Biotechnol. 91(4): 1107-1119. PMID: 21637936

5. Orton, F., Et al. 2012. Environ. Health Perspect. 120(11): 1578-1584. PMID: 23008280

Physical State :
Solid
Solubility :
Soluble in water (1.4 mg/ml), methanol, ethanol, dichloromethane, and hexane (19 mg/ml).
Storage :
Store at room temperature
Melting Point :
50-52° C
Boiling Point :
347° C
Density :
1.35 g/mL at 26° C
Refractive Index :
n20D 1.57 (Predicted)
pK Values :
pKa: 6.53, pKb: 6.74 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
NI4776000
PubChem CID :
37175
Merck Index :
14: 3583
MDL Number :
MFCD00055331
EC Number :
252-615-0
Beilstein Registry :
545683
SMILES :
C=CCOC(CN1C=CN=C1)C2=C(C=C(C=C2)Cl)Cl

Download SDS (MSDS)

Certificate of Analysis

Adobe Acrobat Reader is required to reliably view,
print and comment on PDF documents

Imazalil (CAS 35554-44-0)  Product Citations

See how others have used Imazalil (CAS 35554-44-0). Click on the entry to view the PubMed entry .

Citations 1 to 1 of 1 total

PMID: # 27208383  Nagai, M. et al. 2016. Drug Metab. Dispos.

Citations 1 to 1 of 1 total
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getContent, 114ms
  • QUESTIONS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;
  • bvseo_sdk, java_sdk, bvseo-3.2.0
  • CLOUD, getReviews, 9ms
  • REVIEWS, PRODUCT
  • bvseo-msg: The resource to the URL or file is currently unavailable.;

Santa Cruz Biotechnology, Inc. is a world leader in the development of products for the biomedical research market. Call us Toll Free at 1-800-457-3801.
Copyright © 2007-2020 Santa Cruz Biotechnology, Inc. All Rights Reserved. "Santa Cruz Biotechnology", and the Santa Cruz Biotechnology, Inc. logo, "Santa Cruz Animal Health", "San Juan Ranch", "Supplement of Champions", the San Juan Ranch logo, "Ultracruz", "Chemcruz", "Immunocruz", "Exactacruz", and "EZ Touch" are registered trademarks of Santa Cruz Biotechnology, Inc.
All trademarks are the property of their respective owners.