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IL-2R Antibody (YNRhIL2R) is a mouse monoclonal IgG2a antibody that detects IL-2 receptor in human samples through flow cytometry (FCM). The IL-2 receptor is a crucial multicomponent complex composed of three subunits: α, β, and γ, which are essential for the high-affinity binding of interleukin-2 (IL-2). The α chain primarily facilitates IL-2 binding, while the β and γ chains are vital for both IL-2 binding and the activation of signaling pathways that promote T cell growth and differentiation. Notably, the common γ chain, also known as γc, plays a significant role as a shared subunit among several cytokine receptors, including IL-4R and IL-7R, enhancing their ligand binding capabilities. However, γc cannot bind these ligands independently, underscoring γc′s importance in receptor assembly and function. Anti-IL-2R antibody (YNRhIL2R) serves as an invaluable tool for researchers studying immune responses and potential therapeutic targets in immunology.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-2R Antibody (YNRhIL2R) | sc-73314 | 100 µg/ml | $322.00 |