IL-2R Antibody (NYRmIL-2R): sc-73315

IL-2R Antibody (NYRmIL-2R) is a mouse monoclonal IgG1 antibody that detects IL-2 receptor in mouse samples through flow cytometry (FCM). IL-2 receptor is a crucial multicomponent complex composed of three subunits: α, β, and γ, which are essential for the high-affinity binding of interleukin-2 (IL-2). The α chain primarily facilitates IL-2 binding, while the β and γ chains are vital for both IL-2 binding and the activation of signaling pathways that promote T cell growth and differentiation. The common γ chain, also known as γc, plays a significant role in enhancing ligand binding across multiple cytokine receptors, including IL-4R and IL-7R, although γc cannot bind these ligands independently. This intricate interplay among the subunits underscores IL-2 receptor′s importance in immune responses, as IL-2 receptor not only mediates T cell proliferation but also influences the overall functionality of the immune system. Anti-IL-2R antibody (NYRmIL-2R) serves as an invaluable tool for researchers studying T cell biology and cytokine signaling mechanisms in mouse models.