IL-1 beta/IL1B Antibody (AS57): sc-52771
- IL-1 beta/IL1B Antibody (AS57) is a mouse monoclonal IgG2b, cited in 3 publications, provided at 100 µg/ml
- raised against recombinant IL-1β of human origin
- recommended for detection of IL-1β of human origin by WB and IP
- See IL-1 beta/IL1B (E7-2-hIL1β): sc-32294 for IL-1 beta/IL1B antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for IL-1 beta/IL1B Antibody (AS57). This work is in progress.
IL-1β Antibody (AS57) is a mouse monoclonal IgG2b antibody that detects interleukin-1β in human samples through applications such as western blotting (WB) and immunoprecipitation (IP). IL-1β is a pivotal cytokine that plays a crucial role in mediating inflammatory responses and is primarily produced by activated macrophages, although other cell types, including dendritic cells and fibroblasts, can also secrete IL-1β. IL-1β is synthesized as an inactive precursor, pro-IL-1β, which is then cleaved by caspase-1 to generate the active form. This post-translational modification is essential because active IL-1β initiates and propagates inflammatory signals, making IL-1β a key player in various immune responses. IL-1β dysregulation has been linked to numerous inflammatory diseases, including rheumatoid arthritis and inflammatory bowel disease, highlighting IL-1β importance in both health and disease. Anti-IL-1β antibody (AS57) is an invaluable tool for researchers studying inflammation and immune regulation mechanisms, providing insights into potential therapeutic targets for inflammatory disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
IL-1 beta/IL1B Antibody (AS57) | sc-52771 | 100 µg/ml | $322.00 |